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Traditional Chinese medicine compound preparation for treating sores and ulcers and unknown pyogenic infections as well as preparation method and application thereof

A technology of unknown swollen poison and compound preparation, which is applied in the directions of antiviral agents, pharmaceutical formulations, medical preparations with inactive ingredients, etc. , The effect of reducing swelling of the foot and relieving the degree of inflammation

Inactive Publication Date: 2020-08-21
赵婧
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, Western medicine mostly uses antibiotics combined with hormone therapy for the treatment of the above diseases, and administers oral medicine or intravenous injection. Although it is very effective, it is very easy to relapse after stopping the medicine, and it is easy to become chronic, resulting in prolonged healing.
As for external use, most of them are erythromycin and chlortetracycline antibiotic ointments with very limited effects, but the effect is limited and the curative effect is not good.

Method used

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  • Traditional Chinese medicine compound preparation for treating sores and ulcers and unknown pyogenic infections as well as preparation method and application thereof
  • Traditional Chinese medicine compound preparation for treating sores and ulcers and unknown pyogenic infections as well as preparation method and application thereof
  • Traditional Chinese medicine compound preparation for treating sores and ulcers and unknown pyogenic infections as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] In this example, the medicinal materials of "Zhao's One-shot Elimination" coating agent were analyzed, and the optimal distillation conditions were optimized through the effects of impregnation, different water addition (solid-liquid ratio) and distillation time on the volatile oil content.

[0037] 1 Reagents and instruments

[0038] 1.1 Test drug "Zhao's one-shot" coating agent (Chinese medicinal materials purchased from Tongling Hetian Chinese Medicine Pieces Co., Ltd.).

[0039] 1.2 Instrument Multifunctional extraction tank (Shanghai Jiuyi Xishan Drying Factory), 5mL, 10mL graduated cylinder (Shanghai Shenbo Instrument Company).

[0040] 2 Experimental methods and results

[0041] 2.1 Prescription analysis

[0042] Poplar spikes are the male inflorescences of several species of Populus tomentosa of the Salicaceae plant. Distributed in Liaoning, Hebei, Shanxi, Shaanxi, Gansu, Jiangsu, Anhui, Zhejiang, Henan and other places. Bitter in the mouth, cold in nature, ...

Embodiment 2

[0071] In this example, through different extraction solvents, the best extraction method is optimized based on the yield of the extract of "Zhao's Yiyixiao" as the judging standard.

[0072] 1 Reagents and instruments

[0073] 1.1 Reagent Acetic acid (Sinopharm Chemical Reagent Co., Ltd., 20180704), ethanol (Taicang Xintai Pharmaceutical Ethanol Co., Ltd., 201900301); the rest of the reagents are the same as in Example 1.

[0074] 1.2 Instrument Same as Example 1.

[0075] 2 Experimental methods and results

[0076] 2.1 Preliminary selection of extraction methods

[0077] According to the early understanding of the material basis of the medicinal materials involved in the "Zhao's Yiyixiao" coating agent, starting from the commonly used extraction and separation methods and specific chemical composition of active ingredients in traditional Chinese medicine and natural medicines, the main medicines in the prescription analysis The characteristics of chemical components such as...

Embodiment 3

[0090] In this example, through the design of orthogonal experiments, the amount of water added, the extraction time, and the number of extractions are used as the influencing factors, and the content of chlorogenic acid in the extract of "Zhao's One-shot Elimination" and the evaluation criteria for the yield rate are used to optimize the best extraction conditions.

[0091] 1 Reagents and instruments

[0092] 1.1 Reagent ethyl acetate, petroleum ether, acetone, glacial acetic acid, vanillin, sulfuric acid, xylene (all analytically pure, Sinopharm Chemical Reagent Co., Ltd.); -0301); Negative control samples were extracted voluntarily according to the process; all the other reagents were the same as in Example 3.

[0093] 1.2 Instruments Agilent1260 high-performance liquid chromatography (Agilent Corporation of the United States), JA2003A electronic balance (Shanghai Jingtian Electronic Instrument Co., Ltd., precision 0.001g), ultrasonic instrument (Shanghai Ningshang Ultraso...

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Abstract

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating sore and ulcer and unknown pyogenic infections, which is composed of white poplar spike, saxifraga stolonifera, garden balsam stem, fresh Chinese violet, fresh rehmannia glutinosa, honeysuckle, edible tulip, paris polyphylla, fresh commercial road, myrrh, frankincense, dragon's blood, acacia catechu, pseudo-ginseng, borneol and yellow lead. The invention further provides a traditional Chinese medicine compound preparation for treating sores and ulcers andunknown pyogenic infections and a preparation method and an application thereof. The traditional Chinese medicine compound preparation is mainly used for treating blood stasis swelling and pain caused by nodules of breast, acute mastitis, sore and ulcer carbuncle joints, unknown pyogenic infections, goiter, scrofula, sputum, stubborn dermatitis and traumatic injuries. The swelling and pain are relieved in the early stage of sores and ulcers, the product is capable of extracting pus and drawing out poison in the pus forming stage; in the ulceration period, necrotic tissue is removed, tissue regeneration is promoted, and wounds are protected.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a compound traditional Chinese medicine preparation for treating sores and ulcers and unknown swollen toxins, as well as its preparation method and application. Background technique [0002] Sores, unknown swellings, also known as swellings, carbuncles, and deficient ulcers, are purulent diseases between the skin, muscles, tendons and bones caused by various pathogenic factors invading the human body, including acute and chronic. [0003] At the beginning of acute sores, the skin of the affected area is red and swollen, soft and headless, and the pain is severe. But it quickly agglomerated, showing a slightly raised purple-red infiltrated area, with a tough texture and unclear boundaries. At this time, mild cases have no systemic symptoms, while severe cases may have fever, aversion to cold, headache and nausea. When purulent, the local swelling is high and protrudin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/70A61P15/14A61P17/00A61P17/02A61P31/12A61P43/00A61K31/045A61K33/241
CPCA61K9/7015A61K31/045A61K36/185A61K36/258A61K36/324A61K36/328A61K36/355A61K36/47A61K36/48A61K36/704A61K36/76A61K36/86A61K36/889A61K36/896A61K36/898A61K47/32A61K47/38A61K2236/331A61K2236/39A61P15/14A61P17/00A61P17/02A61P31/12A61P43/00A61K33/241A61K2300/00
Inventor 赵婧赵凤林赵铮赵星
Owner 赵婧
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