Liquid invisible mask with broad-spectrum bacteriostasis as well as preparation method and use method thereof

An invisible and mask technology, applied in medical preparations containing active ingredients, antibacterial drugs, pharmaceutical formulations, etc., can solve the loss of bactericidal effect of modified chitosan and garlic extract, increase economic cost, and safety can not be obtained. security issues

Active Publication Date: 2020-10-27
HUNAN TIANXIANG BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is found in actual research that the stability of the film layer is poor, and the bactericidal effect of the modified chitosan and garlic extract has been lost before being fully brought into play, resulting in the user having to replenish the liquid medicine several times a day, which greatly increases the economic cost; and More importantly, due to the addition of modified chitosan and a large number of auxiliary materials, the safety of long-term use cannot be guaranteed

Method used

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  • Liquid invisible mask with broad-spectrum bacteriostasis as well as preparation method and use method thereof
  • Liquid invisible mask with broad-spectrum bacteriostasis as well as preparation method and use method thereof
  • Liquid invisible mask with broad-spectrum bacteriostasis as well as preparation method and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1 The preparation of a kind of liquid invisible mask

[0045] The formula is as follows: by mass percentage, 85% of garlic extract, 10% of sesame essential oil, and 5% of milk fat cream.

[0046] Concrete preparation steps:

[0047] 1) Refining sesame essential oil in a constant temperature electric heating jacketed pot with stirring at a temperature of 120°C for 20 minutes, then adding milk fat cream, stirring and refining for 10 minutes, and cooling for later use;

[0048] 2) Add the garlic extract to the system obtained in step 1), emulsify and homogenize, and mix evenly;

[0049] Among them, the emulsification homogenization is carried out by a pipeline type high-shear homogeneous emulsifier, and the specific operating conditions are: speed 1450-1500r / min; intermittent operation: start 3min, stop 2min, three consecutive operation units; processing 500- 1000L.

[0050] figure 1 It is a structural schematic diagram of the liquid invisible mask after fil...

Embodiment 2

[0053] Embodiment 2 The preparation of a kind of liquid invisible mask

[0054] The preparation method is the same as that of Example 1, except that the formula is as follows: by mass percentage, 70% of garlic extract, 20% of sesame essential oil, and 10% of milk fat cream.

Embodiment 3

[0055] Embodiment 3 The preparation of a kind of liquid invisible mask

[0056] The preparation method is the same as in Example 1, except that the formula is as follows: by mass percentage, 80% of garlic extract, 15% of sesame essential oil, and 5% of milk fat cream.

[0057] Effect study

[0058] Aspects such as protective effect, safety, irritation are tested to embodiment 1-2 gained liquid invisible mask.

[0059] 1. Antibacterial and virus inactivation

[0060] The test basis is GB15979-2002.

[0061] The sample stoste of table 1 embodiment 1 is to the antibacterial effect of Staphylococcus aureus

[0062]

[0063] The sample stoste of table 2 embodiment 1 is to the antibacterial effect of escherichia coli

[0064]

[0065]

[0066] The sample stoste of table 3 embodiment 1 is to the antibacterial effect of candida albicans

[0067]

[0068] The sample stoste of table 4 embodiment 1 acts on 5min virus inactivation rate test

[0069]

[0070] Table 5 e...

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Abstract

The invention belongs to the technical field of isolation and antibacterial protective materials, and particularly relates to a liquid invisible mask with broad-spectrum bacteriostasis as well as a preparation method and use method thereof. The liquid invisible mask is a film layer covering the surface of mucosa in the nasal cavity, the oral cavity or the throat, and the film layer comprises garlic extract with the allicin content larger than 45%, sesame essential oil and whipping cream; and the mass ratio of the garlic extract to the sesame essential oil to the whipping cream is (70-85): (10-20): (5-10). The garlic extract with the high allicin content is used as an active ingredient, so that the basic effects of sterilization and disinfection are guaranteed; meanwhile, the sesame essential oil is used as a film-forming carrier material, and the whipping cream is used as a framework material; and through the synergistic effect of the three materials, on the premise that the use safetyis guaranteed, while the sterilization and bacteriostasis effects are improved, the adsorbability, the stability and the use comfort of the film layer are remarkably improved, so that the long-actingprotection effect is exerted to the maximum extent, and a remarkable effect is achieved.

Description

technical field [0001] The invention belongs to the technical field of isolation and antibacterial protective materials, and in particular relates to a liquid invisible mask with broad-spectrum antibacterial and its preparation method and use method. Background technique [0002] The nasal cavity is the two gates guarding the respiratory tract. When small particles enter the nasal cavity through the protective mask, some of the particulate matter will be absorbed by the mucous membrane in the nasal cavity and be blocked from the upper respiratory tract. However, due to the limited adsorption capacity, there are still protection loopholes. [0003] The existing commercial masks are mainly divided into cotton masks, medical non-woven masks, activated carbon masks, dust masks, and N95 masks. Among them, cotton masks are suitable for wearing in winter, mainly to prevent freezing. Medical non-woven masks are mainly used to prevent germs, and filter out 90% of 5μm particles, whic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K36/8962A61K47/44A61P11/00A61P31/00A61P31/04
CPCA61K36/8962A61K9/7015A61K9/0043A61K9/006A61K47/44A61P11/00A61P31/00A61P31/04A61K31/10A61K2236/37A61K36/185A61K2300/00A61K36/88A61K2236/51
Inventor 黄译文黄名勇
Owner HUNAN TIANXIANG BIOTECHNOLOGY CO LTD
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