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A preparation method of cubic liquid crystal nanoparticles of panthenol and its application in wash-off products

A technology of nanoparticles and panthenol, which is applied in the field of personal care, can solve the problems of short residence time of panthenol, affect the effect of panthenol on scalp and hair care, and less deposition, so as to improve the residence time, good application prospects, and production low cost effect

Active Publication Date: 2021-04-30
南京泛成生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the particularity of rinse-off products, panthenol stays on the scalp and hair for a short period of time, and the amount of deposition is small, which affects the care effect of panthenol on the scalp and hair

Method used

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  • A preparation method of cubic liquid crystal nanoparticles of panthenol and its application in wash-off products
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  • A preparation method of cubic liquid crystal nanoparticles of panthenol and its application in wash-off products

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Embodiment

[0032] The preparation method of the cubic liquid crystal nanoparticles of panthenol is as follows:

[0033] (1) Glycerol monooleate (GMO) was completely melted at 55-65°C according to the composition ratio described in Table 1 to obtain an oil phase;

[0034] (2) Dissolving D-panthenol, poloxamer 407 (F127) and alkyl glycoside (APG) in water at 50-60°C and mixing completely to obtain an aqueous phase;

[0035] (3) Slowly add the oil phase into the water phase, perform high-pressure homogenization for 5-10 times, and the homogenization pressure is 600-1200 bar to obtain the cubic liquid crystal nanoparticles of panthenol.

[0036] Table 1: Example formulations of cubic liquid crystalline nanoparticles of panthenol (wt %)

[0037]

[0038]

[0039] Ubiquinol is only biologically active in the D form, and DL-Panthenol is half as active as D-Panthenol. Both are applied in the same way. The above examples are all carried out with D-type panthenol, and other materials in t...

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Abstract

The invention discloses a method for preparing cubic liquid crystal nanoparticles of panthenol and its application in wash-off products. The prepared cubic liquid crystal nanoparticles of panthenol include panthenol, liquid crystal materials, surfactants and stabilizers; The mass percent of described panthenol, liquid crystal material, surfactant and stabilizing agent is (0.1-30.0): (1.0-25.0): (2.5-42.0): (0.1-2.0), and this panthenol cubic liquid crystal nanoparticle does not It will reduce the foam performance of rinse-off products, and also has the effect of increasing and stabilizing foam, and can be applied in transparent rinse-off products. The method for preparing panthenol cubic liquid crystal nanoparticles of the present invention has easy-to-obtain raw materials, simple process, stable performance, small particle size and uniform distribution of liquid crystal nanoparticles, low production cost, is beneficial to industrial production, and has good application prospects.

Description

technical field [0001] The invention belongs to the technical field of personal care, and in particular relates to a preparation method of cubic liquid crystal nanoparticles of panthenol and its application in wash-off products. Background technique [0002] Cubic liquid crystals are nanodispersed systems of bicontinuous phases formed spontaneously by amphiphilic lipids and surfactants in water. Amphiphilic molecules stack infinitely in three-dimensional space to form a "honeycomb" structure. There are tiny water channel structures in its network-like cubic lattice. The two water channels are not connected to each other, one is connected to the outer water channel, and the other is Closed, with a huge surface area. This unique internal structure makes it versatile. [0003] Glyceryl monooleate (GMO) is a commonly used liquid crystal material. GMOs are derived from sunflower oil and are natural esters, a biodegradable, non-toxic material. It can form a stable cubic liquid...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/02A61K8/37A61K8/42A61K8/60A61K8/86A61Q5/02A61Q19/10
CPCA61K8/0295A61K8/375A61K8/42A61K8/604A61K8/86A61K2800/413A61Q5/02A61Q19/10
Inventor 樊媛媛
Owner 南京泛成生物科技有限公司
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