A preparation method of cubic liquid crystal nanoparticles of panthenol and its application in wash-off products
A technology of nanoparticles and panthenol, which is applied in the field of personal care, can solve the problems of short residence time of panthenol, affect the effect of panthenol on scalp and hair care, and less deposition, so as to improve the residence time, good application prospects, and production low cost effect
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[0032] The preparation method of the cubic liquid crystal nanoparticles of panthenol is as follows:
[0033] (1) Glycerol monooleate (GMO) was completely melted at 55-65°C according to the composition ratio described in Table 1 to obtain an oil phase;
[0034] (2) Dissolving D-panthenol, poloxamer 407 (F127) and alkyl glycoside (APG) in water at 50-60°C and mixing completely to obtain an aqueous phase;
[0035] (3) Slowly add the oil phase into the water phase, perform high-pressure homogenization for 5-10 times, and the homogenization pressure is 600-1200 bar to obtain the cubic liquid crystal nanoparticles of panthenol.
[0036] Table 1: Example formulations of cubic liquid crystalline nanoparticles of panthenol (wt %)
[0037]
[0038]
[0039] Ubiquinol is only biologically active in the D form, and DL-Panthenol is half as active as D-Panthenol. Both are applied in the same way. The above examples are all carried out with D-type panthenol, and other materials in t...
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