Tissue-engineered alveolar bone tissue and preparation method thereof

A tissue engineering, alveolar bone technology, applied in biochemical equipment and methods, tissue regeneration, tissue culture and other directions, to achieve the effects of reducing medical costs, convenient material acquisition, and easy access
CN112076349AInactive Publication Date: 2020-12-15西安交通大学口腔医院
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
西安交通大学口腔医院
Publication Date
2020-12-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a tissue-engineered alveolar bone tissue and a preparation method thereof. The tissue-engineered alveolar bone tissue comprises a cell polymer containing seed cells and an extracellular matrix and a scaffold material for promoting bone formation through 3D customization. The tissue-engineered alveolar bone tissue can form a new alveolar bone tissue structure in vivo to recover the horizontal or vertical bone height of the alveolar bone. The tissue-engineered alveolar bone tissue has advantages of simple preparation method, shapeability, availability of a variety of seedcells, a large amount of extracellular matrix, and short in vitro culture and preparation period. Compared with other types of alveolar bone technologies existing at present, the tissue-engineered alveolar bone tissue has better biological activity and good biological safety, and can remarkably shorten time for new bone formation.
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Description

technical field

[0001] The invention relates to the technical field of tissue engineering, in particular to a tissue-engineered alveolar bone tissue used for reconstruction and regeneration of alveolar bone tissue and a preparation method thereof, used for site preservation after tooth extraction, and alveolar bone tissue horizontally and vertically Directed bone augmentation. Background technique

[0002] Alveolar bone defects caused by inflammation, trauma or surgery are common clinical problems. Alveolar bone defects can cause facial changes, leading to tooth loosening and loss, which seriously affects the denture restoration of missing teeth in the later stage, and brings great pain to patients. Therefore, exploring the method of alveolar bone defect repair and regenerating bioactive natural alveolar bone is of great clinical significance for patients' facial restoration and tooth restoration.

[0003] At present, there are mainly two types of alveolar bone defect repa...

Claims

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