Novel electrostatic ion trap ion tangential introduction orbit deflection device

Abstract

The invention relates to a novel electrostatic ion trap ion tangential introduction track deflection device which comprises a deflection outer track and a deflection inner track which form a concentric cylinder, the potential of the deflection outer track is higher than that of the deflection inner track, and the deflection outer track and the deflection inner track form an ion high potential storage deflection cavity O-trap. An ion introduction track used for tangentially introducing ion beams is arranged at the outer end of the high-potential storage deflection cavity O-trap, an electrostatic ion trap inner electrode is arranged in the center of the deflection inner track, and the deflection inner track and the electrostatic ion trap inner electrode form an electrostatic ion trap analysis cavity. The deflection inner rail is provided with an ion orbital transfer introduction channel for introducing ions into the electrostatic ion trap analysis cavity. Compared with the prior art, thedevice has the advantages of reducing ion loss, improving signal intensity, being simple to control and the like.

Description

technical field [0001] The invention relates to the technical field of mass spectrometry, in particular to a novel electrostatic ion trap ion tangentially introduced track deflection device. Background technique [0002] The development of electrostatic ion trap mass spectrometer (Orbitrap) is an important progress in mass spectrometry technology in recent years. Orbitrap mass spectrometer plays an important role in proteomics, clinical analysis and detection with its extremely high resolution and sensitivity. However, due to the technological monopoly of foreign companies on the key technology of this type of mass spectrometry instrument, the C-shape-ion trap (C-Trap), its price is high, which limits the popularization and use of this instrument technology in various scientific research institutions and clinical hospitals in my country. [0003] However, the current C-trap introduction device has an obvious disadvantage, that is, the ions are seriously lost during the proc...

AI Technical Summary

Problems solved by technology

However, due to the technological monopoly of foreign companies on the C-shape-ion trap (C-Trap), the key technology of this type of mass spectrometry instrument, its price is high, which limits the popularization and use of this instrument technology in various scientific research institutions and clinical hospitals in my country.

[0003] However, the current C-trap introduction device has an obvious disadvantage, that is, the ions are seriously lost during the process of injecting into the Orbitrap, which makes many low-abundance signals difficult to be detected.

In addition, the ions incident on the Orbitrap need to go through a short stop time so that the central axis voltage can be adjusted to an appropriate value. The control of this stop time is the technical bottleneck of the ion incident on the Orbitrap.

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