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Artificially cultivated phellinus igniarius extract for treating thyroid cancer and preparation method thereof

A technology of artificial cultivation and thyroid cancer, applied in botany equipment and methods, cultivation, plant cultivation, etc., can solve the problems of patients with severe adverse reactions, high toxicity of chemotherapy drugs, and concurrent infection, and achieve the purpose of strengthening the immune function of the body, Shorten the cultivation period and promote the effect of absorption

Inactive Publication Date: 2021-01-08
XUZHOU UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among clinical thyroid cancers, papillary carcinoma is more common in clinical practice. Currently, the drugs used to treat thyroid cancer are mainly chemical drugs. However, due to the high toxicity of chemotherapy drugs, they can not only kill tumor cells, but also non-selectively kill leukocytes and lymphocytes. Cells and other human body's own immune cells, patients often suffer from concurrent infection due to low autoimmunity, and the adverse reactions of patients are large, and the course of treatment is long and the cost is high, which has great limitations in clinical use.

Method used

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  • Artificially cultivated phellinus igniarius extract for treating thyroid cancer and preparation method thereof
  • Artificially cultivated phellinus igniarius extract for treating thyroid cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036]The preparation method of the artificially cultivated Phellinus igniarius fruiting body extract for treating thyroid cancer of the present invention includes the following steps:

[0037](1) Preparation of cultivation bag material: take 20 parts by weight of mulberry branch sawdust, 50 parts by weight of wine waste residue, 10 parts by weight of molasses, 8 parts by weight of aerobic activated sludge particles, 1 part by weight of quicklime, KH2PO4 0.5 parts by weight, mix well to obtain the required cultivation substrate; take the cultivation substrate according to the mass ratio of 50%:50%, add water and mix it, bag it, and set aside;

[0038](2) Mycelium culture: insert 10wt% of Phellinus igniarius mother seed liquid material into the cultivation bag material, and place the inoculated cultivation bag material at a temperature of 26-27°C and air Perform constant temperature culture in a culture space with a humidity of 60-65%. During the period, control the lighting conditions in ...

Embodiment 2

[0043]The preparation method of the artificial cultivated Phellinus igniarius fruiting body extract for treating thyroid cancer of the present invention includes the following steps:

[0044](1) Preparation of cultivation bag material: take 30 parts by weight of mulberry branch sawdust, 30 parts by weight of wine waste residue, 30 parts by weight of molasses, 3 parts by weight of aerobic activated sludge particles, 5 parts by weight of quicklime, KH2PO4 0.2 parts by weight, mix well to obtain the required cultivation substrate; take the cultivation substrate according to the mass ratio of 50%:50%, add water and mix it, bag it, and set aside;

[0045](2) Mycelium culture: insert 10wt% of Phellinus igniarius mother seed liquid material into the cultivation bag material, and place the inoculated cultivation bag material at a temperature of 26-27°C and air Perform constant temperature culture in a culture space with a humidity of 60-65%. During the period, control the lighting conditions in t...

Embodiment 3

[0050]The preparation method of the artificial cultivated Phellinus igniarius fruiting body extract for treating thyroid cancer of the present invention includes the following steps:

[0051](1) Preparation of cultivation bag material: take 25 parts by weight of mulberry branch sawdust, 40 parts by weight of wine waste residue, 20 parts by weight of molasses, 5 parts by weight of activated sludge particles, 3 parts by weight of quicklime, KH2PO4 0.3 parts by weight, mix well to obtain the required cultivation substrate; take the cultivation substrate according to the mass ratio of 50%:50%, add water and mix it, bag it, and set aside;

[0052](2) Mycelium culture: insert 10wt% of Phellinus igniarius mother seed liquid material into the cultivation bag material, and place the inoculated cultivation bag material at a temperature of 26-27°C and air Perform constant temperature culture in a culture space with a humidity of 60-65%. During the period, control the lighting conditions in the cultu...

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Abstract

The invention belongs to the technical field of artificial cultivation of edible fungi, particularly relates to an artificially cultivated phellinus igniarius sporocarp extract for treating thyroid cancer, and further discloses a preparation method of the artificially cultivated phellinus igniarius sporocarp extract. The artificially cultivated phellinus igniarius sporocarp extract for treating the thyroid cancer is obtained by taking phellinus igniarius sporocarp as a raw material for carrying out water body and alcohol precipitation extraction, the obtained extract has the effects of supporting body resistance and promoting immune functions, has an obvious inhibiting effect on in-vivo transplantation of nude mice with human thyroid cancer, can obviously inhibit proliferation of thyroid cancer cells in vitro at the same time, has a good thyroid cancer treatment effect, can relieve the pain of a tumor patient, prolongs the lifetime, improves the life quality of the patient, and bringsa new candidate medicine for treating the thyroid cancer to clinical application, and the extract is a natural extract, and has the advantages of being high in medication safety and low in toxic and side effects.

Description

Technical field[0001]The invention belongs to the technical field of artificial cultivation of edible fungi, and specifically relates to an artificial cultivation of Phellinus igniarius fruiting body extract for treating thyroid cancer, and further discloses a preparation method thereof.Background technique[0002]Phellinus igniarius belongs to Basidiomycotina, Hymenomycetes, Aphyllophorales, Hymenochaeaceae, Phellinu, and Phellinu. The trade names of P.igniarius, P.baumii and P.linteus, usually born in poplar, mulberry, willow, white birch, beech, On the dead standing and standing trees of peach and other broad-leaved trees. Phellinus igniarius is a precious perennial medicinal fungus developed in recent years and has the reputation of "forest gold". According to the "Dictionary of Traditional Chinese Medicine", Phellinus sibiricum can treat gynecological diseases such as bleeding, hemorrhage, vaginal discharge, and amenorrhea; modern medical research also shows that Phellinus sibiri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01G18/00A01G18/20A23L31/00
CPCA01G18/00A01G18/20A23L31/00
Inventor 陈安徽邵颖刘辉巫永华陈尚龙
Owner XUZHOU UNIV OF TECH
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