Liquid microfiltration purification and separation device for biological enzyme preparation

Abstract

The invention belongs to the technical field of biological enzyme preparation equipment and discloses a liquid microfiltration purification and separation device for biological enzyme preparation. The liquid microfiltration purification and separation device for biological enzyme preparation includes a casing, and the front side of the casing is installed horizontally. A liquid inlet pipe is installed, and the middle part of the upper wall of the liquid inlet pipe is fixedly connected with a liquid inlet bucket. The liquid microfiltration purification and separation device for biological enzyme preparation, the suction microfiltration mechanism imitates the working principle of the lungs, and uses the transmission mechanism to change the pressure in the filter box through the movement of the rubber sheet, and can collect and discharge the filtered liquid when pumping the liquid to be filtered Impurities, the change of liquid flow rate and flow direction during the pumping process is different from the stable flow direction of traditional equipment. The continuous change of the position of the microfiltration membrane during this process can also avoid the attachment of impurities on the microfiltration membrane, which greatly increases the efficiency of microfiltration. The continuous working time of the membrane reduces the replacement frequency, thereby ensuring the long-term stable and effective operation of the equipment, and solving the problems raised in the background technology.

Description

technical field [0001] The invention relates to the technical field of biological enzyme preparation equipment, in particular to a liquid microfiltration purification and separation device for biological enzyme preparation. Background technique [0002] Biological enzymes are catalytic organic substances produced by living cells, most of which are proteins, and a very small part is RNA. [0003] During the preparation of biological enzymes, it is necessary to perform microfiltration purification on the biological enzymes extracted in the culture medium in order to obtain higher purity biological enzymes, which are mainly filtered through microfiltration membranes. Microfiltration membranes generally refer to the filtration pore size of 0.1-1 microns Due to the small pores of the microfiltration membrane, the microfiltration membrane is prone to blockage during the continuous microfiltration purification process, and the flow rate drops. The traditional solution is to replace...

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Problems solved by technology

[0003] During the preparation of biological enzymes, it is necessary to perform microfiltration purification on the biological enzymes extracted in the culture medium in order to obtain higher purity biological enzymes, which are mainly filtered through microfiltration membranes. Microfiltration membranes generally refer to the filtration pore size of 0.1-1 microns Due to the small pores of the microfiltration membrane, the microfiltration membrane is prone to blockage during the continuous microfiltration purification process, and the flow rate drops. The traditional solution is to replace the microfiltration membrane, such as the Chinese patent ( Authorized notification number CN 206872822U) discloses a biological enzyme liquid microfiltration purification and separation device. The disassembly structure of the microfiltration membrane is designed to make it easy to replace and save downtime. Replacement after clogging is a stupid method, and it needs to be replaced after each replacement. It will still take a lot of time to clean the equipment and reuse it. How to reduce the replacement operation and reduce the clogging of the microfiltration membrane to ensure the long-term stable operation of the equipment is an urgent problem we need to solve

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