Crude drug composition for preventing or treating respiratory diseases

A technology for respiratory diseases and compositions, applied in the direction of respiratory diseases, drug combinations, pharmaceutical formulations, etc., can solve problems such as untreatable and limited

Pending Publication Date: 2021-01-15
HELIXMITH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this conventional therapeutic agent for respiratory diseases is limited to the treatment of chronic obstructive pulmonary disease (COPD) in infants or children with allergic asthma and smokers
Moreover, most of the above-mentioned therapeutic agents are only used to relieve symptoms, and have limi

Method used

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  • Crude drug composition for preventing or treating respiratory diseases
  • Crude drug composition for preventing or treating respiratory diseases
  • Crude drug composition for preventing or treating respiratory diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0082]Throughout this specification, unless otherwise mentioned, "%" used to indicate the concentration of a specific substance is solid / solid is (weight / weight)%, solid / liquid is (weight / volume)%, and Liquid / liquid is (volume / volume)%.

preparation example 1

[0084]Preparation Example 1: Preparation of compound crude drug extract (mixed extract)

[0085]The washed and dried yam, dandelion and nepeta were used in the experiment. After mixing the crude yam, dandelion, and nepeta crude drugs in a weight ratio of 1:1:1 to make the total weight 60g, add 10 times the 25% (v / v) ethanol aqueous solution to stir well under normal temperature conditions. Hours and extract. The extract is filtered and concentrated under reduced pressure at a temperature of 50 to 65°C, and then freeze-dried to obtain a powdered composite crude drug extract (mixed extract). The yield is about 12-13%.

preparation example 2

[0086]Preparation Example 2: Preparation of compound crude drug extracts (mixed extracts) of various crude drug mixing ratios

[0087]The washed and dried yam, dandelion and nepeta were used in the experiment. After mixing the crude drugs of the above yam, dandelion, and nepeta in the weight ratio (w / w) described in Table 1 to make the total weight 30g, add 10 times the 25% (v / v) ethanol aqueous solution to the room temperature Stir well under the conditions for 8 hours and extract. After filtering the extract and concentrating under reduced pressure at a temperature of 50-65° C., it was freeze-dried to obtain a total of 7 composite crude drug extract powders. The yields are shown in Table 1.

[0088]Table 1

[0089] classification Yam Dandelion Nepeta Yield (%) Preparation Example 2-1 11111.95 Preparation example 2-2 21113.17 Preparation example 2-3 41114.81 Preparation example 2-4 12111.84 Preparation example 2-5 14110.83 Preparation example 2-6 11210.49 Preparation example 2-7 11410.2...

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PUM

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Abstract

The present invention relates to a pharmaceutical composition for preventing or treating respiratory diseases and a food composition for preventing or relieving respiratory diseases comprising a mixedextract of Dioscoreae Rhizoma, Taraxaci Herba and Schizonepetae Spica as an active ingredient. A composition comprising a mixed extract of Dioscoreae Rhizoma, Taraxaci Herba and Schizonepetae Spica of the present invention has an advantage of preventing respiratory diseases and relieving the symptoms of respiratory diseases, restores damages in the lung tissue and has efficacy for inhibiting inflammation, oxidative stress and ageing reactions induced by fine dust. More particularly, the composition of the present invention increases the expression of a telomerase which extends the length of atelomere, and thus is expected to fundamentally treat degenerative respiratory diseases induced by fine dust unlike existing symptom alleviating agents.

Description

Technical field[0001]This application requires the Korean patent application filed on March 16, 2018 and the application number is 10-2018-0031150, and the Korean patent application filed on March 13, 2019 and the application number is 10-2019-0028956 The priority of, its entire content is incorporated in this application by reference.[0002]The present invention relates to a crude drug composition for the prevention or treatment of respiratory diseases, in particular, to a composition containing extracts of Dioscoreae Rhizoma, Taraxaci Herba and Schizonepetae Spica for the prevention, treatment or improvement Composition for respiratory diseases.Background technique[0003]Respiratory diseases are diseases related to the lungs and respiratory tract, which are mainly caused by the inhalation of harmful particles and aging due to reduced immunity, inflammation, bacterial or viral infection, dust or smoking. Representative respiratory diseases include pneumonia (pneumonia), rhinitis, ast...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K36/288A61K36/53A23L33/105A61P11/00A61P11/04
CPCA23L33/105A61K36/288A61K36/53A61K36/8945A61P11/00A61P11/04A61K2300/00A61K36/538A61K2236/333
Inventor 孙美苑裴敏贞李元宇李头奭
Owner HELIXMITH CO LTD
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