Biosensor system and biological sample detection method
A biosensor and sample technology, applied in the biological field, can solve the problems of limited and closed detection of magnetic particles, and achieve the effects of increasing throughput, reliable test results, increasing sensitivity and linear range
Inactive Publication Date: 2021-02-02
绍兴市达冷肯生物科技有限公司
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Problems solved by technology
[0004] In view of this, it is necessary to provide a biosensor system to solve the problem that the existing magnetic particles cannot be closed and detected and the application is limited
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[0052]In order to make the objectives, technical solutions, and advantages of the present invention clearer, the following further describes the present invention in detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention.
[0053]The invention provides a biosensor system, such asfigure 1 ,11,include:
[0054]The biosensor 1 includes a substrate 10 and a magnet assembly 11 arranged in the substrate 10. The substrate 10 has a connecting portion 100 and a microfluidic channel 101 opened inside. The magnet assembly 11 includes two microfluidic channels 101 coated on The magnetic drive layer 110 at the end and a number of electromagnetic particles 111 free in the microfluidic channel 101. The magnetic field strength of each electromagnetic particle 111 can be changed separately through electrical control. The magnetic drive lay...
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The invention relates to a biosensor system, and the system comprises a biosensor comprising a base material and a magnet assembly, wherein the base material has a connection portion and an internallyopened microfluidic channel; the magnet assembly comprises a magnetic driving layer coated on the inner wall of the microfluidic channel and a plurality of electromagnetic particles dissociating in the microfluidic channel, and the magnetic field intensity of the electromagnetic particles can be respectively changed through electric control; the magnetic driving layer has acting force for drivingaway the electromagnetic particles, and the surfaces of the electromagnetic particles are coupled with molecular groups capable of reacting with a to-be-detected substance in a sample and generatingoptical signals. The system also comprises a biosensor box which comprises a box body, a magnetic field forming mechanism and an optical detection mechanism, wherein the magnetic field forming mechanism and the optical detection mechanism are fixed to the box body; the box body is provided with a connecting part connected with the biosensor, the magnetic field forming mechanism forms a variable magnetic field, and the optical detection mechanism is used for detecting optical signals in the biosensor. The biosensor system can provide a more reliable test result.
Description
Technical field[0001]The present invention relates to the field of biotechnology, in particular to a biosensor system and a method for detecting biological samples.Background technique[0002]Pathogenic microorganisms are invisible hazards and have always been a hot issue of people's attention. Their pollution is a major safety issue that seriously affects human health. According to estimates by the World Health Organization, billions of people in the world are infected with diseases each year due to pathogenic microorganisms. The main microorganisms that cause disease include Vibrio parahaemolyticus, Staphylococcus, Salmonella and Bacillus cereus. Chemical contaminants such as clenbuterol and melamine are terrible, but food-borne diseases caused by pathogenic microorganisms are indeed the number one issue of food safety. The detection technology of pathogenic microorganisms is a key technical link in the prevention and control of foodborne diseases caused by pathogenic microorganisms...
Claims
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IPC IPC(8): G01N21/64G01N33/533G01N33/535G01N33/564
CPCG01N21/6428G01N21/6486G01N33/533G01N33/535G01N33/564G01N2021/6439
Inventor 黄国莲李相才程巧霞
Owner 绍兴市达冷肯生物科技有限公司