A kind of anti-fatigue pharmaceutical composition and preparation method thereof
A composition and anti-fatigue technology, applied in the field of biomedicine to achieve the effects of inhibiting oxidative stress, prolonging time and eliminating oxidative stress
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[0042] A method for preparing an anti-fatigue pharmaceutical composition, using active ingredients and medically acceptable excipients to prepare the pharmaceutical composition, the active ingredients are the following raw materials in weight percentages: Astragalus 3-9 parts by weight, Nansha ginseng 3-9 parts by weight, Rehmannia glutinosa 3-9 parts by weight.
[0043] In a preferred embodiment, the preparation method of the pharmaceutical composition comprises the following steps:
[0044] (1) Weigh the raw materials according to the proportion, add ethanol with a mass percentage concentration of 60%, soak at room temperature for 24 hours, perform ultrasonic extraction for 1 hour, filter, and repeat the above extraction steps twice;
[0045] (2) Merge the filtrate three times, recover under reduced pressure, and freeze-dry to obtain extract fine powder;
[0046] (3) adding an appropriate amount of medically acceptable excipients, such as lactose, dextrin, starch, magnesium...
Embodiment 1
[0048] Embodiment 1. (tablet)
[0049] Get 1000g of the medicinal extract of the present invention, add 480g of lactose, 500g of starch and mix evenly, use 7% starch slurry 300g as a binder, wet granulate, dry, add 20g of magnesium stearate and mix, and press into each tablet containing 10000 tablets of extract 100mg, each with a net weight of 0.2g. Take orally, 2 times a day, 3 tablets each time, for anti-fatigue. Symptoms: general fatigue, no improvement after rest.
Embodiment 2
[0050] Embodiment 2. (tablet)
[0051] Get 800g of the medicinal extract of the present invention, add 480g of lactose, 700g of starch and mix uniformly, use 7% starch slurry 300g as binder, wet granulate, dry, add 20g of magnesium stearate and mix, and press into each tablet containing 10,000 tablets of extract 80mg, each with a net weight of 0.2g. Take orally, 2 times a day, 3 tablets each time, for anti-fatigue. Symptoms: general fatigue, no improvement after rest.
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