A high-efficiency extraction and separation device for supercritical fluid used in pharmaceuticals

Abstract

The invention discloses a high-efficiency extraction and separation device for supercritical fluid used in pharmaceuticals, which belongs to the field of supercritical fluid extraction. It prefills the pulverized extracted substance into a shrinkage extrusion bag to expand it, and utilizes the pressure during the extraction process. The increase of the shrinkage extrusion capsule shrinks, and the elastic connecting piece is used to make the plugging ball seal the feeding channel, so that the shrinkage extrusion capsule can squeeze and eject the extracted material from the magnetic sealing sheet, so as to increase the relationship between the extracted material and The contact area of ​​CO2 improves the extraction efficiency, and the flow rate of CO2 is reduced by the retardation ball with a curved channel, so as to prolong the residence time of CO2, increase the contact time between the extracted substance and CO2, and further improve the extraction efficiency. Compared with other technologies, it improves the contact time and area of ​​CO2 and the extracted substance, which greatly improves the extraction efficiency.

Description

technical field [0001] The invention relates to the field of supercritical fluid extraction, in particular to a pharmaceutical supercritical fluid high-efficiency extraction and separation device. Background technique [0002] Supercritical fluid extraction is a new type of extraction and separation technology. It uses a supercritical fluid, that is, a fluid in a thermodynamic state with a temperature higher than the critical temperature and a pressure higher than the critical pressure, as the extraction agent. Extract specific components from liquids or solids for separation purposes. The characteristics of supercritical fluid extraction are: the extractant is a gas at normal pressure and room temperature, and it is easy to separate from the raffinate phase and extraction group after extraction; it operates at a lower density, especially suitable for the separation of natural substances; the pressure can be adjusted Adjust the dissolving ability of the superboundary fluid...

AI Technical Summary

Problems solved by technology

[0004] In order to improve the extraction efficiency, most of the existing supercritical fluid extractors increase the contact time and area between CO2 and the extracted substance by setting a contact plate, but in essence, it is solved from the aspect of CO2. In fact, the particle size of the extracted substance The size is also an important factor affecting the extraction efficiency. At present, there is no device that can improve the extraction efficiency from both CO2 and the extracted substance

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