Bladder cancer pathomics intelligent diagnosis method based on machine learning and prognosis model thereof
A technology of machine learning and intelligent diagnosis, applied in the field of medical artificial intelligence, to achieve the effect of alleviating shortages and accurate prediction
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[0041] Please see attached Figure 1-6 , a machine learning-based pathomics intelligent diagnosis method for bladder cancer and its prognosis model, comprising the following steps:
[0042] Step 1. Data Acquisition:
[0043] The pathological microscopic images of 406 bladder cancer tissues and 37 normal bladder tissues stained with hematoxylin-eosin (H&E) were obtained from the Cancer Genome Atlas bladder cancer database as the training set. At the same time, 108 pathological microscopic images of bladder cancer and 53 normal bladder tissues stained by H&E were obtained from Shanghai First People's Hospital as a test set. Each image was labeled as either a bladder cancer tissue section or a normal bladder tissue section by an expert pathologist.
[0044] Step 2. Micropathology image processing:
[0045] Firstly, 443 training set medical microscopic images and 161 test set pathological microscopic images are magnified by a microscope at 400 times, and then segmented image pr...
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