Method for extracting lacosagenin from liliaceae allium plants
A technology of laxogenin and Allium, which is applied in the direction of steroids and organic chemistry, can solve the problems of high raw material cost, long time consumption, cumbersome processing and extraction process, etc., and achieve low raw material cost, environmental friendliness and excellent preparation process simple effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0022] A method for extracting laxogenin from Liliaceae Allium:
[0023] 1. Rinse 10 kg of freshly harvested Allium sativa whole plant, and then crush it. Put the pulverized material into the reaction kettle, add 20 kg of water and stir to mix evenly. After the mixture was heated to 90°C, it was distilled with steam, and the distillation was terminated when the distillate was no longer turbid.
[0024] Two: centrifuge the distilled mixture while it is hot, and wash the filter cake with 3 kg of hot water at 70°C. The filtrate was extracted with 20 x 2 kg of ethyl acetate, and the extracts were separated and combined and left standing for use. Put the filter cake into 15 kg of ethyl acetate, stir and heat to reflux for 30 minutes, then cool and filter. The filtrate was combined with the aforementioned extract and washed with 5 kg of water. After static phase separation, the ethyl acetate layer was separated and dried with 0.5 kg of anhydrous sodium sulfate. The sodium sulfa...
Embodiment 2
[0029] A method for extracting laxogenin from Liliaceae Allium:
[0030] Step 1 is the same as in Example 1.
[0031] Two: centrifuge the distilled mixture while it is hot, and wash the filter cake with 3 kg of hot water at 70°C. The filtrate was extracted with 20×2 kg of dichloromethane, and the extracts were separated and combined and left standing for use. Put the filter cake into 15 kg of dichloromethane, stir and heat to reflux for 30 minutes, then cool and filter. The filtrate was combined with the aforementioned extract and washed with 5 kg of water. After static phase separation, the dichloromethane layer was separated and dried with 0.5 kg of anhydrous sodium sulfate. The sodium sulfate was removed by filtration and the solvent was concentrated to remove 27 g of a brown viscous concentrate, which was analyzed to contain 1.1 caratsogenin.
[0032] Three: Dissolve the above concentrate in 300 grams of ethyl acetate and add 100 grams of silica gel. Concentrate the so...
Embodiment 3
[0035] A method for extracting laxogenin from Liliaceae Allium:
[0036] Step 1 is the same as in Example 1.
[0037] Two: centrifuge the distilled mixture while it is hot, and wash the filter cake with 3 kg of hot water at 70°C. The filtrate was extracted with 20 × 2 kg of dichloroethane, and the extracts were separated and combined to stand for use. Put the filter cake into 15 kg of dichloroethane, stir and heat to reflux for 30 minutes, then cool and filter. The filtrate was combined with the aforementioned extract and washed with 5 kg of water. After static phase separation, the dichloroethane layer was separated and dried with 0.5 kg of anhydrous sodium sulfate. The sodium sulfate was removed by filtration and the solvent was concentrated to remove 29 g of a brown viscous concentrate which was analyzed to contain 1.7 carats of sapogenin.
[0038] Three: Dissolve the above concentrate in 300 grams of ethyl acetate and add 100 grams of silica gel. Concentrate the solven...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More