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Application and extraction method of caulis spatholobi and caulis spatholobi leguminous similar medicinal materials

A technology of Mildew Spatholobus and Leguminosae, which is applied to the application and extraction of Mildew Spatholobus and similar medicinal materials of Mildew Spatholobus, can solve the problems of large adverse reactions and poor effects, and achieve low cost, simple processing, and enhanced The effect of lowering blood fat

Inactive Publication Date: 2021-04-16
右江民族医学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of sarcopenia is mainly based on functional exercise, nutritional intervention and hormones, etc., but the effect is not good and the adverse reactions are large.

Method used

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  • Application and extraction method of caulis spatholobi and caulis spatholobi leguminous similar medicinal materials
  • Application and extraction method of caulis spatholobi and caulis spatholobi leguminous similar medicinal materials
  • Application and extraction method of caulis spatholobi and caulis spatholobi leguminous similar medicinal materials

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Prepare the extract of Spatholobus and the similar medical materials of Spatholobus Spatholobus, the extraction method comprises the following steps:

[0052] (1) Preparation of extract

[0053] Take Spatholobus Spatholobus as raw material, cut Spatholobus Spatholobus into thin slices, sun-dry or air-dry, take 5kg and use 90%, 50% and 10% ethanol to soak 3 times at 30°C, filter for 72 hours each time, raw material and ethanol The ratio of solution impregnation is: add 1L ethanol solution per kilogram of raw material, stir once every 1h during the impregnation process, the stirring time is 15min, the filtrate is left to settle and the supernatant is taken, combined; the filter residue and sediment are extracted twice with boiling water , 30min each time, precipitate to get the supernatant, combine the supernatants of multiple boiling water extractions; combine the supernatants of ethanol extraction and boiling water extraction to obtain the extract.

[0054] (2) Impurit...

Embodiment 2

[0060] Prepare the extract of Spatholobus and the similar medical materials of Spatholobus Spatholobus, the extraction method comprises the following steps:

[0061] (1) Preparation of extract

[0062] Using Millet Spatholobus as raw material, cut Millet Spatholobus into thin slices, sun-dry or air-dry, take 5kg and use 90%, 50% and 10% ethanol to impregnate 3 times at 50°C, filter each time after 36 hours, raw materials and The ratio of ethanol solution impregnation is: add 1.5L ethanol solution per kilogram of raw material, stir once every 0.5h during the impregnation process, the stirring time is 10min, the filtrate is left to settle and the supernatant is taken, combined; the filter residue is extracted twice with boiling water , each time for 10 min, precipitate and take the supernatant, and combine the supernatants of multiple boiling water extractions; combine the supernatants of ethanol extraction and the supernatants of boiling water extraction to obtain an extract. ...

Embodiment 3

[0069] Prepare the extract of Mildew Spatholobus and the similar medicinal material of Mildew Spathifolia, the extraction method comprises the following steps:

[0070] (1) Preparation of extract

[0071] Take Spatholobus Spatholobus as raw material, cut Spatholobus Spatholobus into thin slices, sun-dry or air-dry, take 1kg and use 90%, 50% and 10% ethanol to soak 3 times at 60°C, filter each time for 12 hours, raw materials and The ratio of ethanol solution impregnation is: add 3L ethanol solution per kilogram of raw material, stir once every 3h during the impregnation process, the stirring time is 30min, the supernatant is taken from the precipitate, and combined; the filter residue and precipitate are extracted twice with boiling water, The supernatant was collected by precipitation for 90 minutes each time, and the supernatants extracted by boiling water were combined; the supernatants extracted by ethanol and the supernatants extracted by boiling water were combined to ob...

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Abstract

The invention discloses application of caulis spatholobi and caulis spatholobi leguminous similar medicinal materials and application of caulis spatholobi and / or caulis spatholobi leguminous similar medicinal materials in preparation of medicines for treating sarcopenia or atherosclerosis. One or more caulis spatholobi and caulis spatholobi leguminous similar medicinal material extracts can be independently adopted or one or more extracts can be matched with other medicinal materials; and the effects of reducing blood fat, improving hemorheology, promoting muscle cell proliferation and the like are achieved through multi-component and multi-target synergistic effects, preventing and treating sarcopenia are achieved, and meanwhile the effects of preventing and treating cardiovascular and cerebrovascular diseases, menstrual diseases, osteoporosis, cough and the like are achieved.

Description

technical field [0001] The invention relates to the technical field of application of traditional Chinese medicines, in particular to the use and extraction method of Spatholobus Spatholobus and similar medicinal materials of Spathiphyllum Fabaceae. Background technique [0002] The traditional Chinese medicine Spatholobus Spatholobus is the rhizome of Spatholobus (Spatholobus) Spatholobus three-leaf Spatholobus (suberectus). It tastes bitter, sweet, slightly warm in nature. It has the functions of activating collaterals, and is mainly used to treat symptoms such as soreness of the waist and knees, numbness and paralysis, and irregular menstruation. Similar medicinal materials of Spatholobus legumes include Spatholobus (Spatholobus) red blood vine (sinensis), Millettia (Millettia) Hainan vine (Spatholobus, pachyloba), Indian vine (Indian chicken blood vine, pulchra), Kunming Millipeda vine (S. network vine, reticulata) original variety, fragrant-flowered vine (Dielsiana, di...

Claims

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Application Information

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IPC IPC(8): A61K36/486A61P21/00A61P9/10A61P9/04A61P15/00A61P9/00A61P7/06A61P19/10A61P11/14A61K125/00
Inventor 杨彩艳王金花周柳芳元辉雄黎飚潘兴寿韦宝敏邓百路史沛钊顾建忠蔡健赵殿臣陆华冠郑晓峰
Owner 右江民族医学院
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