Biosensing device for enhancing antigen and antibody combined optical detection signal

An optical detection and biosensing technology, applied in the direction of color/spectral characteristic measurement, etc., can solve the problems of inconspicuous reflection of light, influence of experimental results, failure to scan, etc.

Inactive Publication Date: 2021-04-30
KUNMING MEDICAL UNIVERSITY
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  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the existing biosensing devices for optical detection signals of antibody and antigen binding, due to the small number of antibodies and antigens in some parts, the light reflection is not obvious, so it is necessary to promote the combination of antibodies and antigens, thereby To avoid errors in the experimental results, and during the scanning process, because most of the light sources are manually moved, it is easy to miss some parts, which will not be scanned, which will affect the experimental results

Method used

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  • Biosensing device for enhancing antigen and antibody combined optical detection signal
  • Biosensing device for enhancing antigen and antibody combined optical detection signal
  • Biosensing device for enhancing antigen and antibody combined optical detection signal

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Embodiment Construction

[0027] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0028] see Figure 1-7 , in an embodiment of the present invention, a biosensing device for enhancing the optical detection signal of the combination of an antigen and an antibody includes an adjustment box 1, a first working box 4 and a second working box 5 are arranged on the top of the adjustment box 1, and the adjustment box 1 The bottom is slidingly connected with a reflection receiving plate 7 and a light emitter 8, one side of the adjustment box 1 is fi...

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Abstract

The invention discloses a biosensing device for enhancing antigen and antibody binding optical detection signals, and the device comprises an adjusting box, wherein a first working box and a second working box are arranged at the top of the adjusting box; by arranging the heating piece, the material box and the metal plate, a solution pump in the material box pumps a solution for reaction into the reaction cavity, a good liquid environment is provided for reaction of antibodies and antigens, regular replacement can be achieved, the activity of liquid is kept, the metal plate is fixed to the bottom in the reaction cavity, and the metal plate is good in material biological compatibility; therefore, the good environment is provided for the antibody-antigen reaction, and the heating sheet can heat the interior of the reaction chamber so as to increase the temperature to the temperature beneficial to the enzyme reaction so as to promote the antibody-antigen reaction; the adjusting box, the second sliding block and the first sliding block are arranged, so the reflection receiving plate and the light emitter can slide at the bottom of the adjusting box at a constant speed, and constant-speed scanning is achieved.

Description

technical field [0001] The invention relates to the technical field of biosensing devices, in particular to a biosensing device for enhancing the optical detection signal of antigen-antibody combination. Background technique [0002] A biosensing device is an instrument that is sensitive to biological substances and converts its concentration into electrical signals for detection. It uses immobilized biosensitive materials as recognition elements, including enzymes, antibodies, antigens, microorganisms, cells, tissues, Nucleic acid and other biologically active substances, and appropriate physical and chemical transducers, such as oxygen electrodes, photosensitive tubes, field effect tubes, piezoelectric crystals, etc., and analysis tools or systems composed of signal amplification devices, biosensors have receivers and converters The function of the molecular recognition part to identify the measured target is the main functional element that can cause a certain physical or...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/35
CPCG01N21/35
Inventor 吴怡卢敏南李树民孔灿
Owner KUNMING MEDICAL UNIVERSITY
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