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Liquid snore-ceasing composition

A composition and liquid technology, applied in the field of medical devices, can solve problems such as respiratory distress

Pending Publication Date: 2021-05-18
茂名市人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a liquid anti-snoring composition to solve the problem of respiratory distress caused by muscle relaxation during sleep

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A liquid anti-snoring composition consists of 0.3wt% theophylline, 3wt% menthol microspheres, 5wt% Tween 80, 20wt% glycerin, 4wt% sodium chloride, 2wt% sodium edetate, 1wt% sorbic acid Potassium, 1 wt% polyethylene glycol, and the remainder deionized water.

[0022] According to the above formula, add Tween 80, glycerin, sodium chloride, sodium edetate, potassium sorbate, and polyethylene glycol into deionized water in sequence, and disperse evenly by ultrasonication for 20 minutes; , Menthol microspheres, just stir evenly.

[0023] The preparation of menthol microspheres is involved in the above formula. It should be indicated that any microsphere preparation technology is likely to prepare the above-mentioned slow-release microspheres. The preparation method selected in this example is based on the continuation of the previous research results. invented.

[0024] Specifically, the preparation method of menthol microspheres is as follows: wash and grind mint leaves, ...

Embodiment 2

[0026] The difference between Example 2 and Example 1 lies in the formula of additives. Specifically, the formula of this implementation is: 0.5wt% of theophylline, 5wt% of menthol microspheres, 5wt% of Tween 80, 30wt% of glycerin, 5wt% % sodium chloride, 3wt% sodium edetate, 1wt% potassium sorbate and 3wt% polyethylene glycol.

Embodiment 3

[0028] The difference between Example 3 and Example 1 lies in the formula of the additive, specifically the formula of this example is: the concentration of theophylline is 0.3wt%; the concentration of menthol microspheres is 3wt%; the concentration of Tween 80 is 3wt%; The concentration of glycerin is 15wt%, the concentration of sodium chloride is 3wt%, the concentration of sodium edetate is 1wt%, the concentration of potassium sorbate is 0.5wt%, and the concentration of polyethylene glycol is 1wt%.

[0029] Trial case and analysis:

[0030] 9 test subjects were recruited in the hospital, including 5 males and 4 females. Each of them used sleep recording software to record their voices in advance. The snoring time of each night was not less than 0.5h. The above snoring time requirements.

[0031] Every night before going to bed, the tester sprayed a liquid anti-snoring composition into the nasal cavity, and recorded the sound with sleep recording software, and the test conti...

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Abstract

The invention aims to provide a liquid snore-ceasing composition so as to solve the problem of respiratory distress caused by muscle relaxation in a sleeping process. The liquid snore-ceasing composition comprises theophylline, menthol microspheres, Tween 80, glycerol, sodium chloride, sodium edetate, potassium sorbate, deionized water and polyethylene glycol, particularly comprises 0.3-0.5wt% of theophylline, 3-5wt% of menthol microspheres; 3-5wt% of Tween 80; 15-30wt% of glycerol; 3-5wt% of sodium chloride, 1-3wt% of sodium edetate, 0.5-1wt% of potassium sorbate, and 1-3wt% of polyethylene glycol.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a liquid anti-snoring composition. Background technique [0002] Obstructive sleep apnea hypopnea syndrome (OSAHS) has gradually entered the field of vision of doctors, patients and researchers with the increase in the number of obese people, rhinitis people, elderly people, and people's attention to health. [0003] The main reason is that in the state of deep sleep, the respiratory distress caused by muscle relaxation affects the quality of sleep, and in severe cases, it will lead to suffocation. Contents of the invention [0004] The object of the present invention is to provide a liquid anti-snoring composition to solve the problem of respiratory distress caused by muscle relaxation during sleep. [0005] Above-mentioned purpose of the invention of the present invention is achieved through the following technical solutions: [0006] A liquid anti-snoring compositi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/522A61K31/045A61K9/08A61K47/26A61K9/52A61K47/36A61P11/00A61P25/20
CPCA61K31/522A61K31/045A61K9/08A61K47/26A61K9/5036A61P11/00A61P25/20A61K2300/00
Inventor 黄金波吕华亮
Owner 茂名市人民医院
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