Anti-infection nasal vestibule covered stent and preparation method and application thereof

Abstract

The invention discloses an anti-infection nasal vestibule covered stent and a preparation method and application thereof, the nasal vestibule covered stent comprises a stent body, the shape and size of the stent body are matched with the shape of a nasal vestibule; and a covering film, wherein the covering film is compounded on the stent body. The stent body has a shape memory function and is well matched with the form structure of the nasal vestibule of a human body. The covering film is composed of at least one fiber layer, and the aperture of the fiber layer is gradually reduced from the lowermost layer of the lower covering film to the uppermost layer of the upper covering film in a gradient mode. The nasal vestibule covered stent provided by the invention can achieve gradient filtration of gas inhaled into a human body through a nose, and achieves the purpose of preventing bronchial, microbronchial and pulmonary infection of an artificial trachea or tracheal stent transplantation patient. The stent is simple in structure, convenient to manufacture, attractive in application and remarkable in anti-infection effect, medicine carrying and medicine releasing of the covered stent can be achieved, and the stent has multiple additional function attributes.

Description

technical field [0001] The invention relates to the technical field of covered stents, in particular to a nasal vestibular covered stent for anti-infection of the respiratory system of patients with tracheal stent placement or artificial tracheal transplantation, and a preparation method and application thereof. Background technique [0002] The trachea is the main organ of the human respiratory system, located between the larynx and the trachea, and mainly performs the function of gas communication. The tracheal epithelium is a pseudostratified ciliated columnar epithelium consisting of ciliated columnar cells and mucus-producing goblet cells. The epithelium is usually covered with mucus and cilia. Mucus keeps the trachea moist and contains substances that fight off bacteria and viruses. The movement of cilia can remove foreign bodies in the trachea, and by directional swinging toward the larynx, viruses, bacteria, dust, etc. inhaled into the trachea can be removed. [00...

AI Technical Summary

Problems solved by technology

[0006] The embodiment of the present application provides an anti-infection nasal vestibular covered stent, which solves the technical problem in the prior art that patients with artificial trachea or tracheal stent transplantation are prone to bronchi, bronchioles and lung infections, and proposes a trachea-oriented stent Place the patient's anti-infection nasal vestibular membrane stent, combine the monofilament braided stent with the 3D membrane with gradient filtration function, prevent the inhalation of small particles such as viruses and bacteria from the source, and reduce the chance of infection in patients

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