Composition of guipi decoction and xylitol
A kind of technology of wood fragrance and prescription, applied in the direction of drug combination, food science, plant raw materials, etc., can solve the problems that are not conducive to quality control and large-scale production, unscientific, increase cardiovascular and cerebrovascular, etc., to achieve good quality control and scale Modernized production and remarkable economic benefits
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[0067] 1.2 The preparation method of the composition: wash with distilled water until clean and dry, Atractylodes Rhizome (decoction piece) 30 000g; Poria cocos (decoction piece) 30 000g; Radix Astragali (decoction piece) 30g 000g; longan meat (decoction piece) 30 000g; jujube seed (decoction piece) 30 000g; ginseng (decoction piece) 15 000g; woody fragrance (decoction piece) 15000g; 12 000g, add 4400g of ginger and 4640g of jujube (maximum particle ≤ 0.1cm), add 10 times the amount of distilled water, decoct twice, 2 hours each time, combine the decoction, filter, concentrate, add ethanol Make the ethanol content be 70%, stir well, reclaim ethanol in the supernatant, add distilled water appropriate amount, add xylitol 3200g respectively; Neotame 0.77g; Sucralose (sucralose); 8.5g; Distilled water of xanthan gum 64g Dissolving solution, mix well, let stand, filter, add distilled water to 160 000ml, pre-sterilize, fill, and sterilize.
[0068] 2. The composition of the present...
Embodiment 1
[0070] Example 1: "Effect of Atractylodes Rhizoma Atractylodes Extract on Learning and Memory and Cortical SOD and MDA Contents of Rats with Vascular Dementia" (Ji Zhihong; Journal of Dalian University; Issue 6, Volume 38, December 2017) pointed out that: Atractylodes Rhizoma Atractylodes (WEA) low-dose and high-dose groups stayed in the original platform quadrant significantly longer than the vascular dementia (VD) rat model group (P<0.05, P<0.01). The content of superoxide dismutase (SOD) increased significantly (P<0.05) in low and high dose groups of WEA, but the content of malondialdehyde (MDA) did not change significantly. The results proved that: WEA can significantly improve the learning and memory impairment of VD rats.
[0071] Table 1 The escape latency and residence time of the original platform quadrant in the water maze test of the water extract of Atractylodes macrocephala.
[0072]
Embodiment 2
[0073] Embodiment 2: "The influence of Poria cocos water extract on learning and memory of mice" (Zhang Min et al.; Journal of Beihua University (Natural Science Edition); the 13th issue of volume 13 in February, 2012) points out: Poria cocos water extract ( TDP) can reduce the number of errors in learning and memory experiments within 5 minutes of scopolamine-induced memory acquisition disorder model mice, and prolong the latency period (P<0.05, P<0.01); can reduce 30% ethanol-induced memory reproduction disorder model mice within 5 minutes The number of errors increases the latency period (P<0.05, P<0.01). The results proved that Poria cocos water extract can improve the learning and memory ability of the learning and memory impairment model mice caused by chemical drugs.
[0074] Table 2 The effect of TDP on the learning and memory of scopolamine-induced memory impairment model mice (stepping method).
[0075]
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