Evaluation method for moyamoya disease operation curative effect

A technology of surgery and smog, which is applied in the field of evaluation of the curative effect of moyamoya disease surgery, can solve the problems of not being able to provide beneficial inspiration for the invention, and achieve the effect of objective and true analysis results, high accuracy, and intuitive analysis methods

Pending Publication Date: 2021-06-15
上海全景医学影像诊断中心有限公司
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Problems solved by technology

[0011] The evaluation work for the therapeutic effect of moyamoya disease needs to obtain progress, but above these existing documents can not provide the enlightenment that is beneficial to the present invention

Method used

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Embodiment

[0045] Example: Combining 99TCm-bishemiethyl ester single photon emission computed tomography and computed tomography cerebral blood perfusion imaging technology, with the help of NeuroGam system and SPSS system to evaluate the curative effect of moyamoya surgery; use Mcnemar chi-square test to compare before and after surgery Visual assessment and NeuroGam quantitative analysis revealed differences in the number of lesions; all statistical analyzes were performed using the SPSS system, and paired t-tests were used to explore whether there were group differences in cerebral blood perfusion before and after surgery.

[0046] In the above, taking the preoperative frontal lobe as an example, the number of frontal lobe lesions with reduced blood perfusion found by visual assessment and NeuroGam quantitative analysis were input into the SPSS system, assuming that the positive result was 1 and the negative result was 0. and NeuroGam evaluation group and frequency as the horizontal ax...

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Abstract

The invention relates to a evaluation method for moyamoya disease operation curative effect, which comprises the following steps of: respectively performing three-dimensional ordered subset expectation maximization reconstruction on pre-operation and post-operation SPECT (Single Photon Emission Computed Tomography) images of the same subject by combining 99TCm-bisemi-ethyl ester single photon emission computed tomography and a computed tomography cerebral blood flow perfusion imaging technology, and importing the images into an SPECTProc workflow; firstly, defining and testing a Talairach boundary; after processing is finished, setting a subject reference group, setting voxel data as correlation, and normalizing the voxel data to the maximum value of the whole brain; and comparing the SPECT brain imaging differences before and after the operation of the same subject, and evaluating the operation curative effect of the moyamoya disease. The preoperative and postoperative visual perfusion results and quantitative perfusion ROI results of the same subject can be visually displayed. The analysis may cover the entire cerebral cortex. The analysis method is visual, easy to learn and use, simple and convenient to operate and more objective and real in analysis result. Statistical analysis can be performed on quantitative data and qualitative data at the same time, it is proved through statistical basis to be superior to visual evaluation, and the credibility of a conclusion is guaranteed.

Description

technical field [0001] The present invention relates to IPC classification G06F electrical digital data processing or G06T image data processing or generation technology, including G06T5 / 00 image enhancement or restoration technology such as establishing a similar figure from bit image to bit image, especially a moyamoya disease operation Methods of assessing efficacy. Background technique [0002] Moyamoya disease is a type of cerebrovascular disease with unknown etiology, characterized by chronic progressive stenosis or occlusion of the bilateral internal carotid artery terminal, anterior cerebral artery, and middle cerebral artery origin, and secondary formation of abnormal vascular network at the skull base disease. Because the abnormal vascular network of the skull base looks like "smoke" on cerebral angiography images, it is called "moyamoya disease". [0003] Moyamoya vessels are dilated perforating arteries that act as compensatory collateral circulation. The clin...

Claims

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Application Information

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IPC IPC(8): G16H50/00G06T7/35
CPCG16H50/00G06T7/35
Inventor 楼菁菁朱玉兆
Owner 上海全景医学影像诊断中心有限公司
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