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Automatic stirring device for magnetic bead reagent and magnetic bead reagent path planning method

A path planning and automatic stirring technology, which is applied in chemical instruments and methods, transportation and packaging, dissolution, etc., can solve problems such as difficult to grasp quality and unstable test results, and achieve the goals of improving binding efficiency, fast dyeing, and reducing usage Effect

Pending Publication Date: 2021-06-25
SUZHOU INST OF TRADE & COMMERCE
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0004] In view of this, it is necessary to provide an automatic stirring device for magnetic bead reagents and a path planning method for magnetic bead reagents to solve the problems of difficult quality control and unstable test results in traditional reagent detection methods

Method used

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  • Automatic stirring device for magnetic bead reagent and magnetic bead reagent path planning method
  • Automatic stirring device for magnetic bead reagent and magnetic bead reagent path planning method
  • Automatic stirring device for magnetic bead reagent and magnetic bead reagent path planning method

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Embodiment Construction

[0032] Preferred embodiments of the present invention will be specifically described below in conjunction with the accompanying drawings, wherein the accompanying drawings constitute a part of the application and together with the embodiments of the present invention are used to explain the principle of the present invention, but not to limit the scope of the present invention.

[0033] see figure 1 and figure 2 The automatic stirring device of the magnetic bead reagent provided by the embodiment of the present invention is used to realize the stirring of the magnetic bead reagent, which is developed based on nanomaterials applied to IVD technology (mainly including nucleic acid detection and immunodiagnosis). The surface of the magnetic nanomaterial is coated with silica, and its surface is negatively charged, so that it repels each other, does not agglomerate, and is easy to disperse in the test sample. It has good high uniformity and high dispersibility, and can be driven ...

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Abstract

The invention relates to an automatic stirring device of a magnetic bead reagent and a magnetic bead reagent path planning method.The stirring device comprises a moving magnetic field excitation device and a signal modulation device; the magnetic bead reagent is located in the moving magnetic field excitation device; the moving magnetic field excitation device comprises three sets of orthogonal Helmholtz coils; and the magnetic bead reagent is positioned in the middle of the three groups of orthogonal Helmholtz coils. The signal modulation device comprises a path planning device and a plurality of current generating devices, wherein the path planning device is connected with the plurality of current generating devices, the current generating devices are in one-to-one correspondence with the Helmholtz coils, and the path planning device is used for performing path planning of the magnetic bead reagent; and the current generating devices are used for generating current signals with corresponding frequencies and magnitudes to the corresponding Helmholtz coils according to the path planning result of the path planning device, so that the magnetic bead reagent performs multi-modal motion according to the path planning result. The problems that the quality is difficult to grasp and the detection result is unstable in a traditional reagent detection method are solved.

Description

technical field [0001] The invention relates to the technical field of immunohistochemical staining, in particular to an automatic stirring device for a magnetic bead reagent and a method for planning a route of the magnetic bead reagent. Background technique [0002] With the update and iteration of medical testing technology and the improvement of detection sensitivity requirements, immunodiagnosis has become the largest subdivision of the in vitro diagnostic (IVD) market in my country. In immunodiagnostic techniques, immunohistochemical staining is an important staining method for detecting pathology. It is a new technology that uses specific antibody with chromogenic agent to mark tissue cells through antigen-antibody reaction, so that the labeled tissue produces a color reaction, and then qualitatively, localizes, and quantifies the corresponding antigen. However, the operation process of the traditional manual detection is cumbersome, the antigen-antibody reaction tim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01F13/08
CPCB01F33/451B01F2101/23
Inventor 黄倩刘静静胡天成李磊沈逸程
Owner SUZHOU INST OF TRADE & COMMERCE
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