Multi-target brain region accurate electrical stimulation method based on dense electrode array

Abstract

The invention discloses a multi-target brain region accurate electrical stimulation method based on a dense electrode array. The method comprises the following steps: collecting T1 weighted MRI head image data; performing tissue segmentation on the acquired MRI head influence data by using FSL software, and segmenting the data into five parts, namely scalp, skull, cerebrospinal fluid, gray matter and white matter; carrying out manual correction on the segmented five parts of tissues; tightly attaching n electrodes to the surface of the scalp, and taking the contact ends of all the electrodes and the scalp upwards by 1 mm to serve as conductive adhesive to obtain a head model with the electrodes; performing finite element triangular patch processing on the head model with the electrode; calculating an electric field distribution matrix at a finite element node of the brain when the unit current intensity is injected into each electrode; and calculating an optimization strategy. According to the multi-target brain region accurate electrical stimulation method, multiple kinds of stimulation of multi-target brain region accurate tDCS can be achieved without repeatedly moving the position of the electric electrode, and the flexibility is higher.

Description

【Technical field】 [0001] The invention relates to an electrical stimulation method, in particular to a precise electrical stimulation method for multi-target brain regions based on a dense electrode array. 【Background technique】 [0002] Transcranial direct current stimulation (tDCS) is a technology that uses a constant small direct current to non-invasively regulate the activity of brain neurons. etc.) have an important supporting role. It uses electrodes placed on the scalp to inject current to depolarize or hyperpolarize the resting potential of neurons. The electric field formed by this stimulation is largely affected by the anatomical structure and biophysics of the individual head, and it is difficult to obtain the required current density field in the target brain region of interest (ROI). If a dense electrode array is used to cover the entire scalp in all directions, the current intensity that each electrode should be injected is calculated through a certain optimi...

AI Technical Summary

Problems solved by technology

[0003] Aiming at the problem that the above method cannot specify the position of the target brain curvature, the present invention provides a precise electrical stimulation method for multi-target brain regions based on dense electrode arrays

Images