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Gargle antibacterial liquid and preparation method thereof

A technology of raw material and glycerin, which is applied in the field of gargle antibacterial solution and its preparation, can solve the problems of mouthwash ulcer, mucosal ulceration, necrosis, etc., and achieve the effect of avoiding the formation of ulcers

Inactive Publication Date: 2021-08-27
济南齐华堂医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At the same time, mouthwash is easy to cause ulcers: long-term use of mouthwash by healthy people will cause imbalance of normal flora in the oral cavity, mucosal ulceration, demembrane and even necrosis, and serious ulcers will form

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A gargle antibacterial liquid and a preparation method thereof, comprising the following raw materials in parts by weight: 50 parts of glycerin, 5 parts of chlorhexidine gluconate, 20 parts of flavoring agent, 3 parts of menthyl lactate, 1 part of preservative, 5 parts of sodium citrate, 2 parts of antioxidant, 40 parts of Tween, 4 parts of hydrogenated castor oil, 3 parts of sodium azulene sulfonate, and 1 part of flavor enhancer.

[0029] The flavoring agent is one of sorbitol, xylitol, edible sweetener and edible sea salt.

[0030] The preservative is potassium sorbate.

[0031] The flavor enhancer is thyme, and the antioxidant is grape polyphenols.

[0032] A kind of preparation method of gargle antibacterial liquid as described above, comprises the following steps:

[0033] S1 material preparation: weighing each raw material according to the weight ratio;

[0034] S2 Preparation of Phase A: Put glycerin and purified water in a tank and heat to 80°C and homogeniz...

Embodiment 2

[0041] A gargle antibacterial liquid and a preparation method thereof, comprising the following raw materials in parts by weight: 75 parts of glycerin, 7 parts of chlorhexidine gluconate, 30 parts of flavoring agent, 5 parts of menthyl lactate, 3 parts of preservative, 6 parts of sodium citrate, 3 parts of antioxidant, 50 parts of Tween, 6 parts of hydrogenated castor oil, 4 parts of sodium azulene sulfonate, 2 parts of flavor enhancer.

[0042] The flavoring agent is a combination of sorbitol, xylitol, edible sweetener and edible sea salt.

[0043] The preservative is dehydroacetic acid.

[0044] The flavor enhancer is thyme, and the antioxidant is grape polyphenols.

[0045] A kind of preparation method of gargle antibacterial liquid as described above, comprises the following steps:

[0046] S1 material preparation: weighing each raw material according to the weight ratio;

[0047] S2 Preparation of phase A: put glycerin and purified water in a tank and heat to 80°C, put...

Embodiment 3

[0054] A gargle antibacterial liquid and a preparation method thereof, comprising the following raw materials in parts by weight: 100 parts of glycerin, 9 parts of chlorhexidine gluconate, 40 parts of flavoring agent, 7 parts of menthyl lactate, 5 parts of preservative, 7 parts of sodium citrate, 4 parts of antioxidant, 60 parts of Tween, 8 parts of hydrogenated castor oil, 5 parts of sodium azulene sulfonate, and 3 parts of flavor enhancer.

[0055] The flavoring agent is a combination of sorbitol, xylitol and edible sea salt.

[0056] The preservative is potassium sorbate or dehydroacetic acid.

[0057] The flavor enhancer is thyme, and the antioxidant is grape polyphenols.

[0058] A kind of preparation method of gargle antibacterial liquid as described above, comprises the following steps:

[0059] S1 material preparation: weighing each raw material according to the weight ratio;

[0060] S2 Preparation of Phase A: Put glycerin and purified water in a tank and heat to 8...

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PUM

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Abstract

The invention discloses a gargle antibacterial liquid and a preparation method thereof. The gargle antibacterial liquid comprises the following raw materials in parts by weight: 50-100 parts of glycerol, 5-9 parts of chlorhexidine gluconate, 20-40 parts of a flavoring agent, 3-7 parts of menthyl lactate, 1-5 parts of a preservative, 5-7 parts of sodium citrate, 2-4 parts of an antioxidant, 40-60 parts of Tween, 4-8 parts of hydrogenated castor oil, 3-5 parts of sodium gualenate and 1-3 parts of a flavor enhancer. The gargle liquid uses the sodium gualenate as a coloring agent, does not form adhesion, does not contain any heavy metal component, and is safe and non-toxic. The menthyl lactate is added as a substitute product of an aromatic, has slight mint fragrance, almost has no taste, but has a lasting and pleasant cooling effect, and is identified as an excellent freshener without adverse reactions such as burning, irritation and pricking.

Description

technical field [0001] The invention relates to the technical field of mouthwash compositions, in particular to a gargle antibacterial solution and a preparation method thereof. Background technique [0002] At present, the microbial flora adhered to the surface of the teeth or other soft tissues of the oral cavity is medically called dental plaque. The accumulation of dental plaque can easily lead to various periodontal diseases. Gargle antibacterial solution has certain antibacterial ingredients, which can help us prevent bacteria from adhering and gathering in various parts of the oral cavity. At the same time, the antibacterial ingredients can penetrate the plaque film, reduce the level of plaque endotoxin and the pathogenicity to the gums. [0003] Using an alcohol-based mouthwash can improve dental health and oral hygiene. It also has breath-freshening benefits, is inexpensive, is easy to use, and alcohol is antiseptic, making it an effective tool against tooth deca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/46A61K8/34A61K8/37A61K8/43A61K8/60A61Q11/00A61P1/02
CPCA61K8/345A61K8/37A61K8/43A61K8/466A61K8/60A61K2800/30A61K2800/432A61Q11/00A61P1/02
Inventor 唐文涛徐衍征
Owner 济南齐华堂医药科技有限公司
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