Application of sambucus williamsii in alcoholic bone remodeling, osteonecrosis and osteoporosis

Abstract

The invention discloses application of sambucus williamsii in alcoholic bone remodeling, osteonecrosis and osteoporosis. The root bark of sambucus williamsii contains a large amount of morroniside, can promote the proliferation of cells for promoting the maximum content of monomers in effective parts for fracture healing, has no toxicity, can well inhibit cell apoptosis, and can change the decrease or increase of the expression of the protein, so the treatment effects on alcoholic remodeling, osteonecrosis and osteoporosis are good; sambucus williamsii leaves are bitter and cool, can activate blood, remove blood stasis and relieve pain and are used for traumatic fractures, rheumatic arthralgia and arthralgia and myalgia; sambucus williamsii flowers are used for sweating and inducing diuresis; and the sambucus williamsii is used for dispelling wind, inducing diuresis, activating blood and relieving pain and is used for rheumatic arthralgia, lumbago, edema, rubella, urticaria, postpartum anemic fainting, traumatic swelling and pain, fracture and traumatic hemorrhage. Therefore, the sambucus williamsii active ingredients have good effects on alcoholic remodeling, osteonecrosis and osteoporosis, and has no toxicity.

Description

technical field [0001] The invention relates to the technical field of use of elderberry, in particular to the application of elderberry in the treatment of alcoholic bone remodeling, osteonecrosis and osteoporosis. Background technique [0002] Osteonecrosis is one of the common orthopedic disabling diseases, and the number of patients is increasing year by year. Carpal bone, lunate bone, tibial tuberosity, metatarsal bone, navicular bone, calcaneus, mandible, femur, etc. can all cause osteonecrosis. There are many causes of osteonecrosis, and femoral head necrosis is the most common in clinical practice. There are about 20 million patients with osteonecrosis of the femoral head in the world, of which my country accounts for about 25%. The number of new patients is 150,000-300,000 every year. About 80% of the patients need artificial joint replacement due to the collapse of the femoral head. Due to the widespread clinical application of glucocorticoids in recent years, it ...

AI Technical Summary

Problems solved by technology

If active treatment is not taken, the vast majority of patients will eventually need to undergo total hip replacement. The treatment costs are high and the trauma is large, which brings a heavy economic burden to patients and the society. What is more serious is that the prosthesis has a certain limitation in lifespan. Sexuality, many patients may need to undergo multiple revisions in their lifetime, seriously impairing the quality of life and working ability of patients, known as "catastrophic disease"