Preparation method of anti-phlegm embolus tracheal catheter loaded with hydrogel coating
An endotracheal tube and hydrogel technology, which can be used in catheters, coatings, pharmaceutical formulations, etc., can solve the problems of reducing the probability of ventilator-related pneumonia, easy blockage and reduction of endotracheal tubes, and reduce cell adhesion and protein. Good adsorption and biocompatibility
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[0024] In order to enable those skilled in the art to better understand the technical solution of the present invention, its specific implementation is described in detail below:
[0025] In an embodiment of the present invention, a method for preparing an anti-phlegm embolism endotracheal tube loaded with a hydrogel coating comprises the following steps:
[0026] S1, the sterilized endotracheal tube is cleaned with isopropanol and deionized water in sequence, and after drying, the inner wall of the endotracheal tube is treated with plasma or ozone;
[0027] S2, immerse the endotracheal tube treated in step S1 into an isopropanol solution containing a hydrophobic photoinitiator for swelling treatment for 1 to 5 minutes, and form a swelling adhesion layer on the inner wall of the endotracheal tube; the hydrophobic photoinitiator is benzophenone, hydrophobic The mass concentration of photoinitiator in isopropanol is 3wt%~10wt%,
[0028] S3, fix an omnidirectional ultraviolet li...
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