A multi-layer medium photoacoustic tomography method
A multi-layer medium, photoacoustic tomography technology, applied in medical imaging, tomography for diagnosis, applications, etc., can solve the problems of complex calculation and low modeling accuracy, and achieve simple solution algorithm and modeling accuracy. High, application-flexible effects
Active Publication Date: 2022-08-09
SOUTHEAST UNIV
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[0004] Aiming at the defects of the prior art, the present invention provides a multi-layer medium photoacoustic tomography method, which solves the current technical problems of low modeling accuracy and complex algorithm calculations for the photoacoustic imaging method
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[0037] The specific embodiments of the present invention will be described below with reference to the accompanying drawings.
[0038] A multi-layer medium photoacoustic tomography method of the present application includes the following steps:
[0039] Step 1, use pulsed light to illuminate the multilayer medium to be imaged, use a plurality of transducers arranged in the outer medium to receive the acoustic signals generated by the multilayer medium from multiple angles and different positions, and analyze each Fourier transform is performed on the signal received by the transducer to form a sound pressure spectrum;
[0040] Step 2, according to the resolution requirements of the required imaging, based on the geometric parameters of the multi-layer medium, perform discretization grid division on the multi-layer medium;
[0041] Step 3, based on the discretization grid division result of step 2, according to the frequency domain sound propagation equation, select a certain ...
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The invention relates to a multi-layer medium photoacoustic tomography method, comprising the following steps: using pulsed light to illuminate the multi-layer medium to be imaged; Receive the acoustic signal generated by the multilayer medium, and perform Fourier transform on the signal received by each transducer to form the sound pressure spectrum; according to the resolution requirements of the required imaging, based on the geometric parameters of the multilayer medium, the The medium is discretized and meshed; according to the sound propagation equation in the frequency domain, a certain number of discrete frequency points are selected to construct a model matrix; the model matrix is combined with the sound pressure spectrum corresponding to a certain number of discrete frequency points to construct a linear equation system; for the linear equation system Perform solution optimization. The imaging method can not only significantly improve the quality of photoacoustic tomography images in multi-layer heterogeneous media and obtain accurate initial sound pressure distribution, but also set the image resolution according to actual needs to complete high-resolution and high-precision imaging.
Description
technical field [0001] The invention relates to the technical field of photoacoustic imaging, in particular to a multi-layer medium photoacoustic tomography imaging method. Background technique [0002] As a new type of non-ionizing imaging method, photoacoustic imaging has the characteristics of optical imaging contrast and acoustic imaging resolution, and is widely used in biomedicine, clinical treatment and other medical fields. In recent years, photoacoustic imaging of multilayer media has attracted the research interest of many experts and scholars, because the inconsistency of acoustic parameters can have a huge impact on imaging. For example, in photoacoustic transcranial imaging, the relationship between skull and brain tissue is The severe acoustic impedance mismatch between the two leads to the amplitude attenuation and phase change of the photoacoustic signal, and these changes will cause serious errors in the reconstructed images using traditional photoacoustic i...
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IPC IPC(8): A61B5/00G06F30/23G06F17/12G06F17/16G06F111/04
CPCA61B5/0042A61B5/0066A61B5/0073G06F30/23G06F17/12G06F17/16A61B2576/026G06F2111/04
Inventor 张辉吴欣恺沈鹏倪中华殷国栋
Owner SOUTHEAST UNIV