The invention discloses a system and method for measuring distribution of strong focused ultrasound nonlinearity sound fields, and belongs to the technical field of ultrasound field measurement. The method comprises the steps that firstly, a distribution curve of the sound pressure in the axial direction of a spherical shell energy converter and a distribution curve of the sound pressure in the radial direction of a focal plane of the spherical shell energy converter are obtained; secondly, the sound pressure distribution curve in the axial direction of the spherical shell energy converter and the sound pressure distribution curve in the radial direction of the focal plane are calculated according to the Rayleigh integral, and the calculating result is compared with the measuring result to obtain a valid parameter; thirdly, the valid parameter is substituted into a nonlinearity sound propagation model to calculate R21, the P0 values are changed, R21 corresponding to different P0 values is calculated, and then the relation curve of R21 and P0 is obtained; fourthly, excitation is exerted on the spherical shell energy converter, the focus waveform is measured to be calculated to obtain R21', and P0' corresponding to R21' is obtained through interpolation; fifthly, P0' is substituted into the nonlinearity sound propagation model, and then the distribution of the nonlinearity sound fields is obtained. The system and method effectively solve the problem that the bandwidth of a hydrophone is insufficient when the hydrophone is used for measuring the nonlinearity sound fields, the relative value R21 serves as a judgment basis, and measuring hidden danger caused by not high sensitivity of the hydrophone is eliminated.