Perillyl alcohol ambradiol carbonate precursor aroma substance as well as preparation method and application of perillyl alcohol ambradiol carbonate precursor aroma substance

Abstract

The invention discloses a perillyl alcohol ambradiol carbonate precursor aroma substance and a preparation method and application thereof. The preparation method comprises the steps of dissolving perillyl alcohol and 1,1'-carbonyldiimidazole in dry tetrahydrofuran, and conducting heating and stirring for a reaction; tracking the reaction endpoint by TLC, after the reaction is completed, adding dichloromethane and deionized water into the organic phase, carrying out liquid separation, removing water from the organic phase by using anhydrous magnesium sulfate, and conducting concentrating to obtain a liquid A; adding ambradiol and N,N-dimethylformamide into the liquid A, conducting heating and stirring to react, and conducting cooling to room temperature after the reaction; and adding deionized water and dichloromethane into the organic phase, conducting liquid separation, washing the organic phase with deionized water and a saturated NaCl solution in sequence, dewatering the organic phase with anhydrous magnesium sulfate, conducting concentrating to obtain oily liquid, and then conducting column chromatography separation and purification to obtain the perillyl alcohol ambradiol carbonate precursor aroma substance. According to the invention, a good model is provided for the application of perfume micromolecules with high volatility and smaller threshold value, the ambergris note and the flower note can be increased and enriched, and the application range of the ambergris raw material and the perilla alcohol is widened.

Description

technical field [0001] The present invention relates to the field of tobacco spices, more specifically, the present invention and a latent aroma substance with ambergris and floral notes based on ambroxol and perillyl alcohol connected by an ester bond and its application in cigarette flavoring. Background technique [0002] Ambergris is a very popular blending spice in the market. It is also known as the four major animal spices together with musk, civet, and kelp. Ambrox ((-)-Ambrox) is a precious raw material of ambergris, which has a strong and special aroma of ambergris. Described as having a "subtle and velvety" ambergris aroma, with an "ambergris effect", it is the soul of ambergris, an excellent fixative, and is the best among all synthetic ambergris fragrances The highest kind. It has been used as a substitute for natural ambergris in high-end perfumes and cosmetic essences. Because it is non-irritating to the human body and has no allergic reactions to animals, i...

AI Technical Summary

Problems solved by technology

It is also used in tobacco flavors, used in tobacco flavors, can enhance the fragrance of flowers, coordinate with the aroma of cigarettes, raise the smoke, improve the taste, but it is not long-lasting, and it is easy to volatilize and lose its characteristics during processing and storage Aroma, does not work well in tobacco formulations

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