Double filtration and adsorption plasma exchange system

Abstract

The invention provides a double filtration and adsorption plasma exchange system which comprises a blood purification channel, a primary plasma separator, a secondary plasma separator and a perfusion device, and the primary plasma separator, the secondary plasma separator and the perfusion device communicate with one another through the blood purification channel. The primary plasma separator is used for separating plasma, the secondary plasma separator is used for filtering macromolecules such as triglyceride in the plasma, and the perfusion device is used for separating, filtering and adsorbing middle molecules such as cell factors in the plasma. According to the double filtration and adsorption plasma exchange system, plasma exchange, hemodialysis perfusion, continuous plasma filtration and adsorption and the like are completed at a time at the same time in the blood purification technology aspect, and great social value and scientific prospects are achieved. Only one blood purification channel, one primary plasma separator, one secondary plasma separator and one perfusion device are needed, cost is low, operation is easy and convenient, and consumed time, manpower, financial resources and the like are low.

Description

technical field [0001] The invention relates to the technical field of blood purification, in particular to a double filtration and adsorption plasma exchange system. Background technique [0002] Severe acute pancreatitis (Severest acute pancreatitis SAP) is a variety of causes that lead to inflammatory damage such as edema, hemorrhage, and necrosis caused by the self-digestion of pancreatic tissue, accompanied by serious complications such as systemic inflammatory response syndrome and multiple organ failure. It is a common critical disease of the digestive system, among which hypertriglyceridemia (HTG) has become a risk factor for SAP, accounting for about 10% of all SAP cases, and hypertriglyceridemia severe acute pancreatitis (HL-SAP) appears younger , severe disease, once the onset, the case fatality rate is as high as about 30-40%, and the annual recurrence rate is as high as more than 50%. The pathogenesis of hyperlipidemia-induced severe acute pancreatitis (HL-SAP)...

AI Technical Summary

Problems solved by technology

Neither plasma exchange, hemodialysis, perfusion, nor continuous plasma filtration adsorption can solve the two core problems of hypertriglyceridemia and cytokine storm at the same time, which makes HL-SAP patients in the critical stage have extremely high risk of disease progression

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