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Bacteriostatic composition, bacteriostatic liquid, application and preparation method

A composition and filtrate technology, applied in the field of skin bacteriostasis, can solve problems such as instability, skin and mucous membrane irritation, etc.

Pending Publication Date: 2022-02-18
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the skin and mucous membrane irritation and instability problems of the current hand bacteriostatic disposable products, the present invention provides a bacteriostatic composition, bacteriostatic liquid, application and preparation method

Method used

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  • Bacteriostatic composition, bacteriostatic liquid, application and preparation method
  • Bacteriostatic composition, bacteriostatic liquid, application and preparation method
  • Bacteriostatic composition, bacteriostatic liquid, application and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～11

[0042] The preparation of antibacterial composition of the present invention: comprise following composition by weight proportioning as shown in table 1 in each embodiment:

[0043] Table 1 Embodiment 1~11 antibacterial composition

[0044]

[0045] In Example 1, the preparation method of the forsythia extract is as follows: ultrasonically extract with 20% v / v ethanol aqueous solution at 30°C: first extract at 30kHz for 25min, and then extract at a frequency of 60kHz for 20min; filter after the extraction is completed, and the obtained Concentrate the filtrate to 1.25g / ml under reduced pressure to obtain final product; wherein, the mass of 20% v / v ethanol aqueous solution is 6 times of that of forsythia;

[0046] The preparation method of the honeysuckle extract is ultrasonic extraction at 50°C with 55% v / v ethanol aqueous solution: first ultrasonic extraction at 30kHz for 25 minutes, and then ultrasonic extraction at a frequency of 60kHz for 18 minutes; after the extractio...

Embodiment 12～22

[0056] The invention provides a no-wash bacteriostatic solution for children's skin and a preparation method thereof: each embodiment includes the following ingredients in proportions by weight as shown in Table 2:

[0057] Table 2 embodiment 12~22 wash-free antibacterial liquid

[0058]

[0059]

[0060] Wherein the preparation method of forsythia extract, honeysuckle extract and citrus extract are the same as in Example 1.

[0061] The preparation method of this antibacterial liquid is:

[0062] Add the moisturizing agent (propylene glycol, butylene glycol and glycerin) in the corresponding formula to the water, heat up to 80°C and stir to dissolve completely;

[0063] Cool down to 50°C, add o-cymene-5-ol and benzalkonium chloride, stir and disperse evenly;

[0064] Cool down to 45°C, add PEG-40 hydrogenated castor oil, honeysuckle extract, citrus extract, essence, disodium EDTA, phenoxyethanol and allantoin, and mix well;

[0065] Lower the temperature to 40°C to o...

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Abstract

The invention relates to the technical field of skin bacteriostasis, in particular to a bacteriostatic composition, application of the bacteriostatic composition, a bacteriostatic liquid prepared from the bacteriostatic composition and a preparation method of the bacteriostatic liquid. The bacteriostatic composition is prepared from the following components by weight: 0.1-0.8 part of a fructus forsythiae extract solution, 0.1-0.8 part of a honeysuckle flower extract solution, 0.1-0.8 part of a citrus extract solution, 0.05-0.15 part of o-cymene-5-alcohol and 0.01-0.08 part of benzalkonium chloride. The bacteriostatic composition is excellent in bacteriostatic effect, mild in property and non-irritant to skin and mucous membranes, and can be prepared into a bacteriostatic washing-free product for sterilizing the skin of children.

Description

technical field [0001] The invention relates to the technical field of skin antibacterial, in particular to an antibacterial composition and its application, an antibacterial liquid made from the antibacterial composition and a preparation method thereof. Background technique [0002] Children's toys and daily clothing are prone to contact with children's sweat and saliva, which can easily breed bacteria. Even products that look clean to the naked eye may have a very high density of bacteria on the surface and inside. Children's hands are in contact with toys, daily clothing and other objects every day, and are the body parts that are exposed to the most bacteria throughout the day. At the same time, children also use their hands to eat snacks or wipe skin products, bacteria on the skin of the hands and between the nails It will enter the body through the hand-mouth route, causing physical discomfort or disease. Therefore, daily protection of children's hand hygiene is nece...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/41A61K8/34A61K8/49A61Q17/00A61Q19/10A61Q17/04A61P17/00A61P31/02A61P31/10A61P31/12A61P31/16A01N65/36A01N33/12A01N31/08A01N25/06A01P1/00
CPCA61K8/9789A61K8/416A61K8/347A61K8/4946A61Q17/005A61Q19/10A61Q17/04A61P17/00A61P31/02A61P31/10A61P31/12A61P31/16A01N65/00A01N65/36A01N65/08A01N33/12A01N31/08A01N25/06A61K2800/522A61K2800/805
Inventor 吴相君冉瑞虎赵美红信璨
Owner SHIJIAZHUANG YILING PHARMA
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