Optical path multiplexing opto-acoustic-white light common-view-field endoscope device and imaging method

Abstract

The invention discloses an optical path multiplexing photoacoustic-white light common-view-field endoscope device and an imaging method. The device comprises a handheld endoscope probe, a laser / optical illumination system and a control and data acquisition and reconstruction system. The handheld endoscope probe comprises a photoacoustic-white light optical path multiplexing assembly, a laser coupling scanning assembly and a photoacoustic-white light detection assembly. The laser coupling scanning assembly is used for focusing and scanning laser, and the photoacoustic-white light path multiplexing assembly is used for generating a photoacoustic signal and a white light reflection signal; the photoacoustic signal is received by the photoacoustic detection assembly, and the white light emission signal is received by the white light detection assembly. The photoacoustic excitation light path and the white light imaging light path share the same path, so that the photoacoustic imaging and the white light imaging realize common-view-field imaging with overlapped imaging centers, and therefore, optical imaging of surface light reflection information and photoacoustic imaging of deep light absorption information can be simultaneously obtained, and the imaging accuracy is improved. And dual-mode common-view-field imaging detection of white light guiding-photoacoustic microscopy is realized.

Description

technical field [0001] The invention belongs to the technical field of endoscope non-destructive testing, and in particular relates to a photoacoustic-white light common-field endoscope device and an imaging method for optical path multiplexing. Background technique [0002] White light imaging technology is to receive white light images through the camera unit after white light illumination, which is an imaging technology for imaging the surface of the imaging area; white light rigid endoscopes are currently widely used in industrial flaw detection, medical imaging and other fields. Conventional equipment, However, since the basic principle is to use the reflection signal to obtain the detection image, it is greatly affected by the scattering of the medium, so it can only image the shallow surface of the imaging area. [0003] Photoacoustic imaging technology means that when pulsed laser light is irradiated into biological tissue, the light-absorbing area in the tissue will...

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Problems solved by technology

[0004] In recent years, many teams at home and abroad have proposed many solutions for photoacoustic endoscopes. Patent No. 201210186582.8 proposes a forward-looking photoacoustic endoscope, which is mainly used for endoscopic imaging of the end face of the target tissue. However, due to the probe The interior contains a piezoelectric scanning device, which cannot achieve miniaturization design, and the vibration caused by the piezoelectric scanning device will form a large noise, which is not conducive to imaging; application number 201711122120.9 proposes a photoacoustic endoscopic microscope based on MEMS mirror Imaging device and its imaging method, the endoscope must shorten the working distance or expand the diameter of the endoscope in order to obtain a sufficient imaging range, it is difficult to scan and image the internal organs or relatively hidden areas of the human body; at the same time, this is a single Mode imaging method, in the application scenario of photoacoustic endoscope, this kind of endoscope has the problem that the positional relationship between the laser and the imaging area in the cavity cannot be observed in real time, and the laser is difficult to accurately irradiate the target imaging area; Patent No. 201310739425.X proposes an endoscope with optical, photoacoustic, and ultrasonic multimode imaging in the rectum and its imaging method. In this solution, an optical camera is equipped in a cannula with a diameter of 12 mm, which is large in size and cannot Photoacoustic imaging and white light imaging achieve common-field imaging in which the imaging center coincides, but it is still difficult to accurately locate the imaging area; at the same time, there is also the problem that the relationship between the laser focus and the imaging area is difficult to determine, resulting in a decrease in resolution

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