Thiamethoxam active compound synthesis process method

Abstract

The invention relates to a process method for synthesizing a thiamethoxam active compound. According to the method, the 2-chloro-5-chloromethylthiazole is used as a raw material and reacts with the 3-methyl-4-nitroimine-1, 3, 5-oxadiazine under the action of the caustic soda flakes as the catalyst to synthesize the thiamethoxam active compound, the synthesis yield reaches 94% or above, and the content of the thiamethoxam active compound reaches 98% or above. According to the reaction device disclosed by the invention, all the materials can reach the reaction temperature during reaction, so that the reaction materials can react under the optimal temperature condition, the defects of the original reaction device are overcome, and the reaction efficiency of the reaction materials is improved.

Description

technical field [0001] The invention relates to a process for synthesizing the original drug of thiamethoxam, which belongs to the technical field of pesticide synthesis. Background technique [0002] Thiamethoxam is a second-generation neonicotinoid high-efficiency and low-toxicity insecticide with the chemical formula C 8 h 10 ClN 5 o 3 S, has stomach toxicity, contact and systemic activity to pests, and is used for foliar spray and soil irrigation and root treatment. It is quickly systemically sucked after application and transmitted to all parts of the plant, and has good control effect on piercing-sucking pests such as aphids, planthoppers, leafhoppers, and whiteflies. [0003] During the synthesis process of pesticides, materials are generally added to the reaction kettle, and then the reaction kettle is heated to the preset temperature for reaction, so that the reaction materials do not reach the reaction temperature condition when they are first mixed, and it tak...

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Problems solved by technology

[0003] During the synthesis process of pesticides, the materials are generally added to the reaction kettle, and then the reaction kettle is heated to the preset temperature for reaction. In this way, the reaction materials do not reach the reaction temperature condition when they are first mixed, and it takes a period of time before they can be heated at the preset temperature. The reaction is carried out at a certain temperature, which will affect the reaction efficiency and needs further improvement

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