Unlock instant, AI-driven research and patent intelligence for your innovation.

Automatic liquid changing device for cell culture

A cell culture, automatic technology, applied in tissue cell/virus culture devices, biochemical cleaning devices, enzymology/microbiology devices, etc., can solve problems such as pollution, achieve simple control, low cost, reduce operating errors and The effect of pollution

Pending Publication Date: 2022-05-24
浙江泰林医学工程有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the disadvantages in the prior art that cell preparation operations are mostly carried out in open cell laboratories, mainly manual operations, the quality of cell preparation is affected by problems such as pollution risks and poor reproducibility caused by manual operations, the present invention provides The automatic liquid change device used for cell culture enables the entire liquid change process to be fully automatic, reducing the risk of operational errors and contamination caused by manual operations

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Automatic liquid changing device for cell culture
  • Automatic liquid changing device for cell culture
  • Automatic liquid changing device for cell culture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] like figure 1 As shown, the automatic liquid exchange device for cell culture includes a fixed table 1, a transfer robot arm 2, a liquid exchange mechanism 3, a petri dish workbench 4, and a needle placement rack 6; the transfer manipulator arm 2 is used to move the petri dish body. 5. The transfer robot arm 2 is set on the fixed table 1; such as figure 2As shown, the transfer manipulator 2 includes a translation mechanism 2.1, a lift mechanism 2.2, a rotation mechanism 2.3 and a transfer plate 2.4, the transfer plate 2.4 is fixed on the rotation mechanism 2.3, the rotation mechanism 2.3 is arranged on the lift mechanism 2.2, and the lift mechanism 2.2 is fixed On the translation mechanism 2.1, the translation mechanism 2.1 and the lifting mechanism 2.2 are rack and pinion mechanisms driven by motors, and the rotation mechanism 2.3 is a motor.

[0032] like figure 1 and image 3 As shown, the liquid exchange mechanism 3 is arranged on the fixed table 1, and the liqu...

Embodiment 2

[0035] like figure 1 and image 3 As shown, on the basis of Example 1, the fixed platform 1 is provided with a waste needle collection box 7, a needle removal block 8 is fixed above the waste needle collection box 7, and several unused suction needles 3.1.5 are neatly arranged arrangement. like Image 6 As shown, the needle removal block 8 is provided with a limit groove 8.1 adapted to the suction needle 3.1.5, and a positioning column 13 is provided around the waste liquid discharge bucket 12, and the positioning column 13 is fixed with the fixing table 1 . A snap ring 3.1.4 is provided on the outer side wall of the liquid aspiration needle 3.1.3, and the liquid aspiration needle 3.1.3 is clamped to the liquid aspiration needle 3.1.5 on the liquid aspiration needle 3.1.3 through the snap ring 3.1.4. A waste needle collection box 7 is arranged on the fixing table 1, and a needle removal block 8 is fixed above the waste needle collection box 7. The needle removal block 8 is ...

Embodiment 3

[0038] like Figure 5 As shown, on the basis of Embodiment 1, the culture dish workbench 4 includes a fixed base 4.1 and a rotating base 4.2 arranged side by side, the fixed base 4.1 is fixed with the fixed base 1, and the rotating base 4.2 is rotatably connected with the fixed base 1. The rotating shaft 4.3 of the seat 4.2 is arranged parallel to the horizontal plane, and the fixed table 1 is provided with a rotary driver 4.5 for driving the rotating seat 4.2 to rotate. When changing the liquid, the culture dish body 5 is placed on the rotating seat 4.2. The rotating shaft 4.3 of the rotating base 4.2 is eccentrically arranged below the rotating base 4.2, and a rotating damper is provided on the rotating shaft 4.3. The rotating driver 4.5 includes an electromagnet, the electromagnet is fixed under the rotating base 4.2, the rotating shaft 4.3 is arranged between the center of gravity of the rotating base 4.2 and the electromagnet, and the lower end of the rotating base 4.2 is...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an automatic liquid changing device for cell culture. The automatic liquid changing device comprises a fixed table; the transfer mechanical arm is used for moving the culture dish body, and the transfer mechanical arm is arranged on the fixed table; the liquid changing mechanism is arranged on the fixing table, the liquid changing mechanism comprises a needle head module and a moving driving mechanism used for moving the needle head module, the needle head module comprises a fixing block, a liquid adding needle tube and a liquid sucking needle tube, the liquid adding needle tube and the liquid sucking needle tube are fixed to the fixing block, and a liquid sucking needle head is arranged on the liquid sucking needle tube; the culture dish workbench is used for placing the culture dish body. According to the automatic liquid changing device for cell culture, full-automatic liquid changing is achieved in the whole liquid changing process, and the risk of operation errors and pollution caused by manual operation is reduced.

Description

technical field [0001] The present invention relates to the technical field of cell medium exchange equipment, in particular to an automatic medium exchange device used for cell culture. Background technique [0002] At present, cell preparation operations are mostly carried out in open cell laboratories, mainly manual operations, and cell preparation personnel need to be trained. Problems such as contamination risk and poor reproducibility caused by manual operation affect the quality of cell preparation. In addition, the manual operation efficiency is low, and the medium usually needs to be changed several times during the entire cell preparation cycle, which requires a lot of labor to complete this work, which is also one of the reasons for the high cost of cell preparation. If automation can be used to replace manual labor in the process of cell exchange, the risk of cell exchange contamination will be reduced, and the exchange efficiency will be greatly improved. Ther...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/32C12M1/00
CPCC12M23/46C12M23/48C12M33/04
Inventor 陈军峰赵振波夏信群叶大林
Owner 浙江泰林医学工程有限公司