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Composition containing panthenol and skin care product

A technology of composition and skin care products, which is applied in the field of A61Q, can solve the problems of reduced efficacy of skin care products, reduced efficacy of skin care products, and reduced panthenol content, etc., and achieves the effects of improving effectiveness, excellent water retention capacity, and alleviating the hydrolysis of panthenol Effect

Active Publication Date: 2022-06-03
凡可生物技术(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, panthenol is extremely easy to hydrolyze, which reduces the efficacy of skin care products, and the problem of panthenol hydrolysis has not yet been solved. The skin care product has a certain anti-aging effect, but after a period of time, the content of panthenol in the skin care product is significantly reduced, so that the efficacy of the skin care product decreases as time goes by

Method used

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  • Composition containing panthenol and skin care product
  • Composition containing panthenol and skin care product
  • Composition containing panthenol and skin care product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0033] An aqueous solution containing a panthenol composition, the specific components are as follows in Table 1, and the unit is parts by weight.

[0034] Table 1

[0035]

[0036] The preparation method is as follows: mix all the ingredients, and get the product.

[0037] Panthenol stability test: use a conductivity tester to measure the conductivity of the panthenol composition in the initial state, measure the content of panthenol by HPLC, and test the conductivity and content every other month. The test cycle is 8 months. The panthenol content obtained by the test is as follows in Table 2 and figure 1 (where ①, ②, ③, and ④ represent Example 1, Example 2, Example 3, and Example 4, respectively), and the electrical conductivity is shown in Table 3 below. Wherein the panthenol content in Table 2 is the percentage content of the measured panthenol weight in the added amount (5 parts by weight).

[0038] Table 2

[0039] Example 1 Example 2 Example 3 ...

Embodiment 5-7

[0044] A moisturizing essence, the specific components are as follows in Table 4.

[0045] Table 4

[0046]

[0047]

[0048] After blind testing and sensory evaluation, the moisturizing essence obtained in Example 6 had better skin feel.

[0049] Water retention test: select 5 volunteers, use the skin water loss (TEWL) test probe to test the transdermal water loss TEWL (marked as T1) of the face before using the product, and then each volunteer Use 1 mL of the moisturizing essence of Example 6 once in the morning and evening, and test the transdermal water loss TEWL on the face at 48h, 7 days, 14 days, 21 days, and 28 days, and test 5 times for each volunteer in each time period , the results are averaged, see Table 5 and figure 2 .

[0050] table 5

[0051]

[0052] from Table 5 and figure 2 The results show that the moisturizing essence in this application has a good effect of retaining water and locking water.

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Abstract

The invention relates to the technical field of A61Q, in particular to a panthenol-containing composition and a skin care product. The panthenol-containing composition comprises panthenol, a hydrogen ion buffer component, succinic acid diethoxyethyl ester and a rutin derivative. According to the application, the 4-hydroxyethylpiperazine ethanesulfonic acid is compounded with the diethoxyethyl succinate, so that the hydrolysis of the panthenol is effectively relieved, the content of the panthenol can be kept for a long time, and the effectiveness of the skin care product is improved.

Description

technical field [0001] The present invention relates to the technical field of A61Q, and more particularly, the present invention relates to a panthenol-containing composition and a skin care product. Background technique [0002] Vitamin B5, namely pantothenic acid, is a water-soluble vitamin. It participates in the metabolic cycle of the human body by converting it into coenzyme A. Panthenol is provitamin B5. Compared with pantothenic acid, it is more easily absorbed by the body and can be effective on the stratum corneum. It has excellent penetrating effect and excellent moisturizing effect. At the same time, it can stimulate the growth of skin epidermal cells and accelerate the healing of wounds. It is suitable for dry skin, oily skin, firm skin, wrinkled skin, sensitive skin, etc. It is widely used in skin care products. [0003] However, panthenol is extremely easy to be hydrolyzed, which reduces the efficacy of skin care products, and the problem of panthenol hydrolys...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/42A61K8/46A61K8/37A61K8/34A61K8/60A61K8/67A61K8/73A61K8/81A61Q19/00
CPCA61K8/42A61K8/466A61K8/37A61K8/67A61K8/602A61K8/8182A61K8/345A61K8/60A61K8/735A61Q19/00A61K2800/592
Inventor 彭冠杰李扬思何水莲陈展辉
Owner 凡可生物技术(广州)有限公司