Unlock instant, AI-driven research and patent intelligence for your innovation.

Circulating tumor cell capture kit

A technology for capturing reagents and tumor cells, applied in biomass post-processing, internal accessories, bioreactors/fermenters for specific purposes, etc. Reasonable, convenient storage and transportation

Pending Publication Date: 2022-08-09
JIANGSU CELL TECH MEDICAL RES INST CO LTD
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The number of CTCs in peripheral blood is very rare, accounting for only 1 / 106-1 / 107 of peripheral blood leukocytes. Therefore, the bottleneck and difficulty of effective enrichment and detection technology for different types of CTCs are higher and more difficult, which has always affected the actual situation of CTCs. application
The current capture kits for CTCs are difficult to achieve the functions of capturing and detecting in one

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Circulating tumor cell capture kit
  • Circulating tumor cell capture kit
  • Circulating tumor cell capture kit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The capture and detection of existing CTCs kits are often limited to the capture and detection of a single group of CTCs, and cannot detect epithelial-mesenchymal mixed CTCs. Due to the heterogeneity and dynamic evolution of CTCs, single-type capture and detection Detection kits greatly limit the clinical application of CTCs.

[0035] like figure 1 and figure 2As shown, a circulating tumor cell capture kit includes a kit box body 1 and a kit box cover 2 that is covered with the kit box body 1, and a capture device 3 is provided inside the kit box cover 2, The inner bottom of the kit body 1 is provided with a micro-control circuit board 4, an operation bottom plate 5 is provided on the micro-control circuit board 4, and a placement slot and a placement hole are arranged in the operation bottom plate 5, and the placement slot is A sample placement vessel 6 is provided, and a reagent bottle group 7 is provided in the placement hole.

[0036] The principle of use of the...

Embodiment 2

[0042] The temperature in traditional CTC capture kits is not suitable enough to cause the blood to freeze easily.

[0043] like figure 1 and figure 2 As shown, a circulating tumor cell capture kit includes a kit box body 1 and a kit box cover 2 that is covered with the kit box body 1, and a capture device 3 is provided inside the kit box cover 2, The inner bottom of the kit body 1 is provided with a micro-control circuit board 4, an operation bottom plate 5 is provided on the micro-control circuit board 4, and a placement slot and a placement hole are arranged in the operation bottom plate 5, and the placement slot is A sample placement vessel 6 is provided, and a reagent bottle group 7 is provided in the placement hole.

[0044] The reagent bottle group 7 includes a cell separation solution reagent bottle, a washing buffer reagent bottle, an antibody diluent reagent bottle, a dye A reagent bottle, a dye B reagent bottle, a dye C reagent bottle, a dye D reagent bottle, and...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a circulating tumor cell capture kit, which comprises a kit body and a kit cover covering the kit body, the inner side of the kit cover is provided with a capture device, the bottom in the kit body is provided with a micro-control circuit board, the micro-control circuit board is provided with an operation bottom plate, and the operation bottom plate is connected with the kit body. A placement groove and a placement hole are formed in the operation bottom plate, a sample placement vessel is arranged in the placement groove, and a reagent bottle group is arranged in the placement hole. The problem that an existing CTCs capture kit is difficult to integrate capture and detection is solved.

Description

technical field [0001] The invention relates to the field of in vitro cell culture devices, in particular to a circulating tumor cell capture kit. Background technique [0002] Circulating Tumor Cells (CTCs) are tumor cells released into the peripheral blood circulation from solid tumors or metastases spontaneously or due to diagnosis and treatment operations. CTCs are mainly heterogeneous populations consisting of epithelial CTCs, epithelial-mesenchymal mixed CTCs and mesenchymal CTCs subsets. [0003] Tumor metastasis is the leading cause of cancer progression and related death. CTCs play an important role in the process of tumor formation and metastasis. If the blood of patients with malignant tumors contains a large number of CTCs, it indicates a poor prognosis and an increased probability of tumor metastasis. Tumor metastasis induced by CTCs mainly involves two dynamic processes, Epithelial to Mesenchymal Transition (EMT) and Mesenchymal to Epithelial Transition (MET...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B65D51/24B65D25/10C12M1/26C12M1/24
CPCB65D51/24B65D25/108C12M33/04C12M23/06
Inventor 杨美家尹鸿萍缪应花王岩
Owner JIANGSU CELL TECH MEDICAL RES INST CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com