Medicine for treating acute ischemic cerebral apoplexy and its preparing method

Abstract

The medicine for treating acute ischemic cerebral apoplexy is prepared with butyl benzene phthalein, emulsifier, co-emulsifier, excipient and water for injection in certain proportion. The preparation process includes weighing materials in certain proportion; mixing butyl benzene phthalein, emulsifier and co-emulsifier in partial water for injection via high speed stirring; dissolving the excipient in other water for injection, adding active carbon, heating at 100 deg.c for 15 min before eliminating carbon; mixing two kinds of solution, adding active carbon, filtering and eliminating carbon; adding water for injection to full amount, measuring pH value and content; fine filtering, bottling and freeze drying to obtain the powder for injection. The present invention provides medicine for salvage of serious cerebral apoplexy patient clinically.

Description

technical field [0001] The invention relates to a pharmaceutical preparation, in particular to a medicine for treating acute ischemic stroke and a preparation method thereof. Background technique [0002] The chemical name of butylphthalide is dl-3-n-butylphthalide. Butylphthalide is the left-handed form extracted from celery seeds, which is then artificially synthesized into a racemic form. Butylphthalide has pharmacological effects against cerebral ischemia. At present, the oral preparation of butylphthalide - butylphthalide soft capsules is listed. The indication of butylphthalide soft capsules is the treatment of acute ischemic stroke. Stroke is a neurological disorder caused by reduced blood flow in a specific blood vessel supplying the brain lasting more than 24 hours, and the final result is cerebral infarction. The morbidity, mortality, and disability rates of stroke are high, which imposes a great burden on families and society. With th...