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Safflower drop pills and preparation method thereof

A technology of safflower and dripping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems that are not conducive to improving the patient's ability to seek medical treatment, the medicinal solution is turbid, and cannot be used, and achieves improved bioavailability. The effect of speeding up dissolution and absorption, and increasing stability

Inactive Publication Date: 2007-04-04
SHANDONG WOHUA PHARMACEUTICALS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] (3) Do not use if the liquid is found to be turbid, precipitated, discolored, or leaked.
[0023] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0049] Now with several groups of specific examples, the preparation method of the safflower dropping pills of the present invention will be further described.

[0050] Group 1: Tests with a single matrix

[0051] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then prepare the dry powder of the extract containing the active ingredients of the traditional Chinese medicine safflower according to the section [Appendix: a preparation method of a traditional Chinese medicine extract] for later use;

[0052] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0053] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:9;

[0054] 4. Then prepare according to the proce...

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PUM

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Abstract

The invention relates to a medicinal oral preparation of safflower with the functions of improving blood circulation and relieving stasis, treating cranial vascular diseases, coronary disease and vasculitis, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administering, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to a kind of pharmaceutical composition which has the effect of promoting blood circulation and removing blood stasis, and is used for treating obliterative cerebrovascular disease, coronary heart disease, vasculitis and other diseases. An oral preparation. Background technique [0002] Safflower is an annual or biennial herb of Compositae, containing safflower glycosides, safflower quinones and neosafflower glycosides. According to the drug standard WS issued by the national ministry 3 - The safflower injection prepared according to the formula and extraction process given in B-3825-98, the main active ingredients are safflower yellow pigment and flavonoids, it is a kind of safflower injection used for the treatment of obliterative cerebrovascular disease, coronary heart disease , pure traditional Chinese medicine injections for diseases such as vasculitis, have been clinically verified for many years, have stable quali...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/286A61P9/10A61P9/14A61K135/00
Inventor 曲韵智
Owner SHANDONG WOHUA PHARMACEUTICALS CO LTD
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