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Sea-buckthorn whole fruit agent and its preparing method and use

A technology of sea buckthorn and fructose, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as hindering the physiological activity of natural plants, destroying the organic composition of natural substances, and defects in production processes, etc. Good biological activity, good physiological activity, high content effect

Inactive Publication Date: 2007-08-01
山西省林业科学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The first is to simply quantify and mix various extracts, which destroys the organic composition of natural substances, so it hinders the full use of the unique physiological activities of natural plants.
Secondly, in the previous introduction to the current production and preparation methods of seabuckthorn products, it can be clearly seen that the ingredients in the patented product include seabuckthorn pomace oil, seabuckthorn fruit oil, and seabuckthorn flavonoids. There will be organic solvent residues or toluene, xylene and other toxic substances that come off from the macroporous resin, causing fatal problems to the product

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] 120 kg of seabuckthorn whole fruit with 8% water content, passed through SCC-10 far-infrared microwave combined negative pressure drying equipment, dried at 60°C for 10 minutes, crushed to 40 mesh by a pulverizer, and passed through SFE-300 supercritical CO 2 Extraction equipment, supercritical CO 2 Extract to obtain 20 kg of non-polar and weakly polar oily extract, and keep it for subsequent use. The remaining 92 kg of seabuckthorn filter residues were extracted with 500 liters of 92% edible ethanol in a 50°C insulation tank for 10 hours, centrifuged to recover ethanol, and dried at 60°C for 25 minutes under negative pressure through SCC-10 far-infrared microwave combined drying equipment , to obtain 16 kg of powdery crude extract with medium and strong polarity. The crude extract was subjected to SFE-100 supercritical CO 2 Extraction pilot equipment, at 35MPa, 60°C, flow rate 300kg / h, analysis pressure 8MPa, analysis temperature 40°C for binary supercritical fluid e...

Embodiment 2

[0049] 120 kg of seabuckthorn whole fruit with 8% water content, passed through SCC-10 far-infrared microwave combined negative pressure drying equipment, dried at 60°C for 10 minutes, crushed to 20 mesh by a pulverizer, and passed through SFE-300 supercritical CO 2 Extraction equipment, supercritical CO 2 Extract to obtain 20 kg of non-polar and weakly polar oily extract, and keep it for subsequent use. The remaining 92 kg of seabuckthorn filter residues were extracted with 500 liters of 95% edible ethanol in a 50°C insulation tank for 12 hours, centrifuged to recover ethanol, and dried at 60°C under negative pressure for 25 minutes through SCC-10 far-infrared microwave combined drying equipment , to obtain 16 kg of powdery crude extract with medium and strong polarity. The crude extract was subjected to SFE-100 supercritical CO 2 Extraction pilot equipment, at 35MPa, 60°C, flow rate 300kg / h, analysis pressure 10MPa, analysis temperature 35°C for binary supercritical fluid ...

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PUM

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Abstract

The present invention provides whole sea-buckthorn fruit essence with all the effective components of natural sea-buckthorn fruit and its extraction process and medicinal use. The extraction process includes drying and crushing sea-buckthorn fruit into 10-60 mesh powder; supercritical CO2 extraction to obtain the initial extractive; extracting the filter residue of the above step with ethanol solution and drying to obtain coarse extractive; binary supercritical fluid extraction of the coarse extractive and low temperature drying to obtain secondary extractive; mixing the initial extractive and the secondary extractive; and homogenizing to obtain the whole sea-buckthorn fruit essence. The whole sea-buckthorn fruit essence has excellent physiological activity and may be used in preparing medicine for treating hepatitis.

Description

technical field [0001] The present invention relates to seabuckthorn whole fruit extract, a method for preparing the extract and the use of the extract. Background technique [0002] The fruit of seabuckthorn contains a variety of physiologically active ingredients and has a wide range of medicinal value. The Chinese Pharmacopoeia clearly states that it has the effects of "relieving cough, eliminating phlegm, digesting food and dissolving stagnation, promoting blood circulation and dispelling blood stasis". In long-term medical practice, people often use it to treat cough, chronic bronchitis, chest tightness, indigestion, stomach pain, bruises, bruises, amenorrhea and other diseases. With people's in-depth research on seabuckthorn fruit, it is found that seabuckthorn not only has the above traditional medical uses, but also has a series of functions such as regulating human immune function, anti-tumor, anti-radiation, anti-fatty liver and cirrhosis, regulating blood lipids,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P1/16A61P31/12A61K131/00
Inventor 张素华王巨成周学仁刘玉成苏琳邹元生聂勇王岳
Owner 山西省林业科学研究院
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