Application of scutellaria root extract in preparation of anti esophageal cancer medicine

Abstract

An application of the scutellaria extract in preparing the medicine for esophagus cancer is disclosed, and it features that scutellarin, scutellaroside, or their mixture can be used to prepare the pharmacologically receptable sale for suppressing the splitting of cancer cell, inducing the withering of cancer cell and inhibiting the generation of the blood vessel inside esophagus cancer.

Description

technical field [0001] The invention relates to the application of the extract of Scutellaria baicalensis, especially the application of the extract of Scutellaria baicalensis in the preparation of anti-esophageal cancer drugs. technical background [0002] From the long-term census of esophageal cancer cases, the development process of esophageal cancer cells is from mild hyperplasia to severe hyperplasia. Carcinoma in situ and invasive carcinoma develop slowly from mild hyperplasia of esophageal mucosa to carcinoma in situ. It is believed that this evolution process takes about 5 to 10 years. Once invasive cancer is formed, its development speed is quite fast. When the patient has obvious symptoms of swallowing obstruction, the cure rate here is very low. The treatment of esophageal cancer is still mainly based on surgery and radiotherapy. Due to the relatively large toxic and side effects on the human body, chemotherapy is only used as an auxiliary means. However, the cu...

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Problems solved by technology

And because the vast majority of patients with esophageal cancer are already in the advanced stage when they are diagnosed, not only the local lesions have been extensively infiltrated, but also the distant spread of subclinical lesions or lymph node metastasis have been found. Autopsy found that many cases that were considered to be locally early died at the time of death. More than half of them have distant metastasis, more than 70% have extensive lymph node invasion, and less than 1 / 3 of the cases can be curatively resected. The 5-year survival rate of conventional radiotherapy is only 13%. The main cause of failure accounts for more than 80%. It can be seen that the treatment of esophageal cancer is far from enough by surgery and radiotherapy alone.

However, these studies are still in the very early stage, and the mechanism of anticancer effect of Scutellaria baicalensis extract is not clear yet.

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