Externally applied agent for relieving inflammation and antibiosis

An anti-inflammatory, antibacterial, and topical medicine technology, applied in the field of external medicine, can solve the problems of skin tissue necrosis, different curative effects, and unfavorable dry scabs on the wound surface, so as to inhibit the exudation of inflammatory edema, prevent progressive necrosis, and promote scab formation healing effect

Inactive Publication Date: 2004-08-11
云南龙发制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these conventional methods have their scientifically advanced side, they still have the following deficiencies in clinical practice: one is to use ointment and cream drugs on the wound surface, which can moisturize, but it is not conducive to dry and scab on the wound surface, which is easy to Prolong the course of the disease by causing necrosis of residual skin tissue on infected wounds
The second is that electric baking wounds can only cure the symptoms. Although it can temporarily solve the dry scab on the wound surface, progressive necrosis (that is, infection under the scab) is very easy to occur under the scab. Muscle is easy to build an artificial natural barrier for bacterial growth, especially the infection of Pseudomonas aeruginosa, so that patients with moderate and severe injuries may suffer unnecessary disability or death due to sepsis or hypertoxemia.
The third is that changing the dressing will bring pain to the patient, and even cause artificial damage to the wound surface, and will increase the consumption of sanitary materials (gauze, cotton wool, adhesive plaster) at the same time
Then there are common gynecological inflammations in clinical practice, such as vulvar itching, yellow discharge, leucorrhea increase and other diseases caused by gonorrhea, fungal vaginitis, cervicitis, etc. Although there are many Chinese and Western medicines for treating such diseases, there are many single medicines , but the curative effect is different, and the phenomenon of repeated attacks is prominent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] 1. Crushing the following raw materials:

[0101] 140 grams of knotweed,

[0102] Alum 0.8 g,

[0103] gypsum 32 grams;

[0104] 2. Add 1000ml of 55% medical ethanol to the above raw materials, soak for 3-5 hours, extract the soaking liquid, filter, sterilize, and package to obtain liniment for external use.

[0105] The total solid content of each 1ml liniment is not less than 0.8-1.2%, the relative density of the liquid medicine is not less than 0.8523-0.9923, and the emodin is not less than 0.05mg.

Embodiment 2

[0107] 1. Crushing the following raw materials:

[0108] 200 grams of knotweed,

[0109] 8 grams of alum,

[0110] 40 grams of gypsum;

[0111] 2. Add 1000ml of 55% medical ethanol to the above raw materials, soak for 3-5 hours, extract the soaking liquid, filter, sterilize, and package to obtain liniment for external use.

Embodiment 3

[0113] 1. Crushing the following raw materials:

[0114] 170 grams of knotweed,

[0115] 5 grams of alum,

[0116] gypsum 36 grams;

[0117] 2. Add 1000ml of 55% medical ethanol to the above raw materials, soak for 3-5 hours, extract the soaking liquid, filter, sterilize, and package to obtain liniment for external use.

[0118] Table 1. Classification by burn wound depth

[0119] Group I degree to superficial II degree (%) Deep II degree (%) III degree (%) Total

[0120] Treatment group 55 cases (55) 36 cases (36) 9 cases (9) 100 cases

[0121] Control group 19 cases (63.33) 11 cases (36.67) 30 cases

[0122] Table 3. Sanyangpi Dai treatment results

[0123] Group Cured (%) Improved (%) Ineffective (%) Most cured Most cured Average cured Total markedly effective

[0124] Long days Short days More days Rate

[0125] Treatment group 87(87) 3(3) 10(10) 11 4 8.16 90**

[0126] Contro...

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PUM

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Abstract

An externally-applied Chinese medicine for anti-inflammatory and antibacterial purposes is prepared from giant knotweed rhizome, alum, gypsum and alcohol. Its advantages are broad spectrum and sure curative effect.

Description

technical field [0001] The invention relates to an external medicine, in particular to an anti-inflammatory and antibacterial external medicine capable of treating burns and scalds. Background technique [0002] So far, in the treatment of burns, scalds, skin and mucous membrane sores, yang syndrome, and traumatic wound infection, in addition to taking or injecting antibiotics, cream or ointment is often used for dressing the wound, and electric baking is also used for large-area burns and scalds. Although these conventional methods have their scientifically advanced side, they still have the following deficiencies in clinical practice: one is to use ointment and cream drugs on the wound surface, which can moisturize, but it is not conducive to dry and scab on the wound surface, which is easy to Causes necrosis of residual skin tissue on the infected wound and prolongs the course of the disease. The second is that electric baking wounds can only cure the symptoms. Although ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P17/02A61P31/02
Inventor 李朝斌
Owner 云南龙发制药股份有限公司
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