Medicine for treating tuberdulosis and lung disease and its preparing method

A technology for tuberculosis and drugs, applied in the field of drugs for treating tuberculosis and lung diseases, can solve the problems of expensive drugs, yellow color, low bactericidal and antibacterial effects, etc.

Inactive Publication Date: 2004-09-29
杨尚星
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the treatment of tuberculosis, countries around the world currently implement a western medicine chemotherapy regimen based on isoniazid and rifampicin combined with 2-5 anti-tuberculosis drugs. However, isoniazid and rifampin are used alone or in combination3 After one month, the drug resistance will increase month by month, and the bactericidal and antibacterial effects will decrease significantly. Continuous drug use will cause neurotoxicity and liver and kidney damage. The urine of patients with tuberculosis drugs is yellow. Continuous drug use can lead to drug-induced hepatitis, renal failure and other diseases. It needs to be used in combination with drugs that protect the liver and kidney. Streptomycin has strong auditory neurotoxicity. Continuous drug use can lead to lifelong deafness and hearing loss. These toxic and side effects and the emergence of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Raw material: black bone 500kg;

[0085] Production method: take 500kg of black bones, add 12 times the weight of water to decoct three times; add 6 times the weight of water for the first time, soak for 8 hours, boil for 2 hours, add 3 times the amount of water for the second time, boil for 2 hours, third Add 3 times the amount of water each time, boil for 1.5 hours, combine the filtrate, filter it while it is hot, let it stand for clarification for 10 hours, take the supernatant liquid for mechanical pressure filtration, further purify its active components according to the existing separation and purification technology, and concentrate the purified medicinal liquid Dilute thick paste (specific gravity 1.05-1.15, thermal test 60°C), spray dry to make fine powder, add appropriate amount of 95% ethanol to moisten the fine powder, granulate, pick up and test, pack into capsules, or add 3-10% Excipients (dextrin, etc.), compressed into tablets, and packaged.

Embodiment 2

[0087] Raw materials were weighed according to the ratio of the example: black bone 375kg, astragalus 75kg, radix radix 50kg.

[0088] Production method: Add the above-mentioned raw materials black bone, astragalus, and Ophiopogon japonicus, add water and boil three times, add 6 times the weight of water for the first time, soak for 8 hours and then boil for 2 hours, add 3 times the amount of water for the second time and boil for 2 hours, the third time Add 3 times the amount of water each time and boil for 1.5 hours, combine the liquid medicine for three times, filter while it is hot, let it stand for clarification for 8 hours, take the supernatant liquid for mechanical pressure filtration, concentrate the filtrate into a thin thick paste (specific gravity 1.05-1.35, 60c), spray dry Make fine powder, add 95% ethanol to moisten the powder, granulate, test, fill capsules, pack, and get ready.

Embodiment 3

[0090] Raw materials were weighed according to the ratio in the following example: black bone 300kg, astragalus 90kg, Radix Ophiopogon japonicus 60kg, Chuan Fritillaria 50kg.

[0091] Production method: Grind the above-mentioned raw materials Fritillaria sichuanensis through 100 meshes for later use; decoct black bones, astragalus, Radix Ophiopogon japonicus, and water for three times, add water 6 to 7 times the weight of the total amount of the three raw materials for the first time, soak for 5 Boil for 2 hours after 8 hours, add 3 to 4 times the total amount of the three raw materials for the second time and boil for 1.5 to 2 hours, add 3 to 4 times the total amount of the three raw materials for the third time and boil for 1.5 to 2 hours, and combine the filtrates , filter while it is hot, let it stand for clarification for 8-10 hours, take the supernatant and filter it mechanically, concentrate the filtrate to a thick paste (specific gravity 1.05-1.10, thermal measurement 6...

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PUM

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Abstract

The medicine is capsule or tablet prepared with forrest silkvine root, astragalus root and ophiopogon root as material through unique preparation process. It has the functions of resisting cystic disease, killing tubercule bacillus, tonifying deficiency and bacteriostasis. It has unique curative effect on tuberculosis and lung-originated heart disease and no medicine resistance. It has effective components for strengthening body's immunity, such as cardenolide, baicalin A, astagalus polysaccharide, etc.

Description

technical field [0001] The invention relates to a medicine for treating tuberculosis and lung disease, specifically a Chinese patent medicine prepared from Chinese herbal medicines, mainly used for treating tuberculosis (and other tuberculosis), pneumonia, pulmonary edema, and acute and chronic bronchitis. It also relates to a preparation method of the medicine. Background technique [0002] Tuberculosis is an ancient global chronic infectious disease. Before the 1840s, it was a highly contagious and difficult-to-cure disease. Since the advent of streptomycin, isoniazid, rifampicin and other anti-tuberculosis drugs , the cure rate of tuberculosis has reached over 95%, and the case fatality rate has dropped below the control line. Since the 1980s, tuberculosis has made a comeback around the world, and the epidemic has rebounded. The main reason is: affected by the biological variation of tuberculosis strains, highly effective anti-tuberculosis drugs such as isoniazid, strept...

Claims

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Application Information

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IPC IPC(8): A61P31/06
Inventor 杨尚星
Owner 杨尚星
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