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Tablet preparation of balsamiferous blumea leaf and branchlet

A technology of cinnamon cinnamon tablets and cinnamon cinnamon tablets, which is applied in the field of preparations of cinnamon cinnamon cinnamon, can solve the problems of excessive addition of auxiliary materials, large granules, and easy moisture absorption and deterioration, and achieves the goal of preparing The method is scientific and reasonable, the therapeutic effect is good, and the storage is convenient

Inactive Publication Date: 2005-01-26
张明亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the amount of excipients added is too much, and the effective substances of Diangui Ainaxiang in the medicine are limited, so the therapeutic effect is not ideal
Moreover, the granules are bulky, easy to absorb moisture and deteriorate, and have poor stability. They need to be taken after boiling water, and are inconvenient to carry, use, and store.
Excipients contain a lot of sucrose, not suitable for diabetics
In addition, Diangui Ainaxiang extract powder is prepared into soft capsules, but the extract powder is water-soluble, difficult to disperse in oil, and the preparation process is difficult to control

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Take 5 kg of Yunnan Gui Ainaxiang medicinal material, add water to decoct twice, each time add 10 times of water to decoct for 1 hour, combine the decoction, filter, concentrate to a relative density of 1.10 (60°C), let stand for 8 hours, filter, The filtrate was spray-dried to obtain dry extract powder, the dry extract powder was sieved, 180 g of microcrystalline cellulose and 15 g of sodium carboxymethyl starch were added, mixed uniformly, dry granulated by a method known in the art, and 5 g of magnesium stearate was added, Tablets, ready to use.

Embodiment 2

[0027] According to the same method as in Example 1, change "spray drying of the filtrate" to "after the filtrate is concentrated into a thick paste, dry under reduced pressure and pulverize".

Embodiment 3

[0029] According to the same method as in Examples 1 and 2, Eudragit E100 was used as a coating material for the prepared tablet, and film-coated to prepare a film-coated tablet.

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PUM

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Abstract

The invention provides a tablet preparation of balsamiferous blumea leaf and branchlet by using balsamiferous blumea leaf and branchlet as the raw medicinal material, mixing with medicinal auxiliary material by proportion, preparing granule through dry method palletizing or wet method palletizing, charging lubricating agent, pressing into tablet, performing film dressing to obtain the tablet.

Description

technical field [0001] The invention relates to a preparation of Ainaxiang Diangui, in particular to a tablet of Ainaxiang Diangui and a preparation method thereof. technical background [0002] Diangui Ainaxiang is a kind of Chinese herbal medicine grown in minority areas in southwest my country. It has the effects of promoting blood circulation, removing blood stasis, stopping bleeding and regulating menstruation. It is mainly used to treat women's menorrhagia and other diseases. In the prior art, the amount of excipients added is too much, and the effective substances in the medicine are limited, so the therapeutic effect is unsatisfactory. And the granules are bulky, easy to absorb moisture and go bad, have poor stability, need to be taken after mixing with boiling water, and are inconvenient to carry, use, and store. The excipients contain a lot of sucrose and are not suitable for diabetics. In addition, the extract powder of Ainaxiang Diangui is prepared into soft ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/28A61P15/00
Inventor 张明亮
Owner 张明亮
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