Nasal spray for treating headache and hemicrania and its preparation method

Abstract

The invention relates to a nose cavity spraying agent for curing headache and migraine and its manufacutirng method. The prescription includes medicine effective ingredients and accessories, the effective ingredients of the medicine is made up of 1-10 shares of chuanxiong rhizome extract, asarum extract and mint extract, the extraction of the effective ingredient may be steam distilling extract method or supercritical fluid extraction method, then the accessories are dissolved in the solution waterless alcohol, then adds in the effective ingredients of each medicine, they are blended fully and poured into the nose cavity spraying pump, the nose cavity spraying agent uses the rich mucous and vessels in the nose cavity, the absorption of the medicine is quick, the biology utilization rate is high, the effect is prominent, and it has no propellant, it does not use pressure resisting container, the atomization drop is tiny, it is even in the nose cavity.

Description

technical field [0001] The invention relates to a drug dosage form, in particular to a nasal cavity administration dosage form for treating headache and migraine. Background technique [0002] Headache is one of the common clinical symptoms, and every adult may have experienced it in a mild or severe manner. Specifically, headache refers to pain or non-painful discomfort in a certain part of the face or head and neck, inside or outside the skull. It has many causes, some of which are serious and fatal, but the etiological diagnosis often causes difficulties. At present, those with headache as the main symptom can be found in infectious febrile diseases, hypertension, intracranial diseases, neurosis, concussion and migraine. Migraine usually occurs in adolescence, and some patients have a family history, which is mostly induced by fatigue, emotional factors, and menstrual periods. Currently in Italy, nearly one in six people suffer from migraines. ...

AI Technical Summary

Problems solved by technology

The dosage form is simple to configure and does not require a special drug delivery device. It is especially suitable for a small amount of self-made application by medical staff in clinical practice. Loss, etc.; aerosol is better in terms of therapeutic effect, absorption speed and bioavailability, but because its aerosol contains propellant, it will cause environmental pollution, and the aerosol must use a pressure-resistant container, and the production process is more complicated