Local externally applied itch stopping garlic paint

A technology of varnish and garlic, which is applied in antifungal agents, medical preparations containing active ingredients, skin diseases, etc. It can solve the problems of inconvenient application and ineffective antipruritic effect, and achieves low price and obvious and rapid antipruritic effect , Good antipruritic effect

Inactive Publication Date: 2005-06-22
TIANJIN GREENPINE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this bath agent is applied on the skin before bathing, and then washed off after bathing, instead of being applied on the skin as an external drug, leaving it on the itchy area, the antipruritic effect is not obvious, and the application is very inconvenient, so it can only be used before bathing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0040]Preparation of pressed garlic bulb juice: 100g of mature garlic bulbs, grind and press the juice, place the garlic juice at 4°C or room temperature for more than 10 hours, filter out the sediment, and obtain 50ml of clarified garlic juice, which can be used directly or diluted with appropriate water. Prepare topical varnishes.

example 2

[0042] Grind 100g of mature garlic bulbs, add 200ml of pure water at 65±5°C, stir for 2 hours, place at room temperature and filter to obtain a water extract. Place the extract at 4°C for 8 hours, or stand at room temperature for 12 hours, centrifuge and filter to remove the precipitate, and obtain 180ml of clear water extract, which can be directly used to prepare paint, or concentrated under reduced pressure to prepare concentrated extract or solid extract Then prepare the topical paint.

example 3

[0044] Grind 100g of mature garlic bulbs, add 500ml of 70% ethanol aqueous solution, stir at 75±5°C for 4 hours to extract, place at room temperature, filter to remove garlic residue, place the extract at 4°C for 6 hours, filter to remove sediment, and depressurize the clarified solution Ethanol was evaporated, and pure water was added to 200ml. The water was left at room temperature for 10 hours, and the precipitate was removed by centrifugation to obtain an extracted water, which could be directly used to prepare external antipruritic varnish or further concentrated under reduced pressure to obtain an extract concentrate (Viscous semi-solid or solid) and then prepare external paint.

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PUM

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Abstract

The invention provides a partially externally used relieve itching epithem and its preparation process, wherein the epithem employs garlic as the principal active composition, the preparation comprises selecting fresh ripened garlic bulb or haulm or scape and disintegrating, charging different solvent, steeping or mixing, extracting 0.5-12 hours at 20-90 deg. C, stewing 10-20 hours at 4-25 deg. C, decompressing and concentrating, and mixing the extract and right amount of medicinal adjuvant.

Description

technical field [0001] The invention relates to an external preparation containing traditional Chinese medicine ingredients, in particular to a topical antipruritic varnish with garlic or its extract as the main active ingredient. Applied to the itchy part of human skin, it can produce obvious and rapid antipruritic effect. Background technique [0002] Skin itching is a problem that people often encounter in daily life. Skin itching caused by various reasons, such as senile skin pruritus, atopic dermatitis itching, foot skin itching caused by athlete's foot, skin itching caused by allergies, etc. Widespread and recurring symptoms. Skin redness, swelling and itching caused by mosquito bites in summer is even more unavoidable. Skin itching, although not life-threatening, but frequent episodes of itching cause great discomfort to people, seriously affecting people's work and sleep. In the past, the treatment of this disease was mainly aimed at the cause, such as rash and it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P17/00A61P17/04A61P31/10
Inventor 王传
Owner TIANJIN GREENPINE PHARMA
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