Organic germanium-base quinolinate compound and its synthesis method
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
- Publication Date
- 2005-06-22
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention belongs to an organic germanium quinoline ester compound and a synthesis method thereof. Background technique
[0002] Since 1968, Japanese scholar Asai Yiyan and others have synthesized water-soluble β-carboxyethyl germanium sesquioxide-(GeCH 2 CH 2 COOH) 2 o 3 , that is, Ge-132, and since its anti-cancer, anti-virus, anti-aging and other biological effects were discovered, the synthesis of new organic germanium compounds and the research on anti-cancer activity have become an important field for people to develop high-efficiency and low-toxicity anti-cancer drugs. People have synthesized many Ge-132 derivatives, containing -GeO 3 Various types of organic germanium compounds, such as Ge-132 analogues of the group, bridge oxygen germanium ring compounds, etc., have studied their anticancer effects in many aspects. Since the 1970s, Japan, the United States, the former Soviet Union, China and other countries have successively synthesiz...