Streptomycin molecular engram solid phase extraction column and preparing process and application thereof

Abstract

This invention discloses a streptomycin module trace solid extraction small column and its process method, which comprises the following: polymer material model module of streptomycin, function single methacrulic acid, and cross linker two methacrylic acid glycol ester combined. It is a cross linked polymers fixed with hole distribution function group, which has the memory function to the streptomycin module space structure and high selection isolation and concentration to the remaining analyzed liquid.

Description

technical field [0001] The invention relates to the field of analytical chemistry, in particular to a streptomycin molecularly imprinted solid-phase extraction column and a preparation method thereof and the purification and enrichment of a sample solution applied to the determination of residual amounts of aminoglycoside antibiotic streptomycin in animal foods . Background technique [0002] Streptomycin is an aminoglycoside antibiotic. It has strong antibacterial effect, but also has strong toxicity. With the rapid development of my country's aquaculture industry, the phenomenon of drug abuse in the aquaculture process is relatively common, which has also resulted in high levels of drug residues in animal-source foods, which are very harmful to human health through long-term enrichment in the food chain. In recent years, with the expansion of breeding scale and the improvement of intensification, the breeding output has been increasing, and th...

AI Technical Summary

Problems solved by technology

At present, the detection method of streptomycin residues in animal food mainly adopts microbial method, which has the disadvantages of long time consumption, low sensitivity, poor accuracy and stability; other methods have complicated sample pretreatment process and poor anti-interference ability; and Can not be in line with international requirements and standards; solid phase extraction method for pretreatment, although the method is simple and convenient, but C 18 Solid-phase extraction cartridges cannot separate streptomycin and other endogenous small molecule interference components in animal-derived foods well