Method for preparing ginsenoside RH2

Abstract

The present invention relates to the preparation of ginsenoside, and especially the preparation process of ginsenoside RH2. The present invention features that the preparation process includes extraction of red ginseng in ethanol; separating and extracting the red ginseng extracting liquid; separating and purifying red ginseng extracting liquid to obtain total ginsenoside; hydrolyzing total ginsenoside to obtain ginsenoside Rg3; enzyme converting ginsenoside Rg3 and low temperature drying to obtain ginsenoside RH2. The present invention has reasonable technological process, high yield and low cost, and is suitable for industrial production.

Description

technical field [0001] The invention belongs to a preparation method of ginsenoside, in particular to a kind of ginsenoside RH 2 method of preparation. Background technique [0002] Ginseng belongs to Panax ginsengC.A.Meyer of the family Araliaceae. In Chinese tradition, it is believed to have the functions of regulating the balance of yin and yang, nourishing body fluids, and regulating the gastrointestinal tract. Ginsenoide (GS) is the main extract. GS has been proven to have various effects on the enhancement of immunity, especially the enhancement of the differentiation activity of phagocytic cells and the increase of the concentration balance of Lysozyme in plasma. The main component of ginseng is saponin, which can improve memory function and enhance immunity. And anti-aging effect, ginsenoside RH 2 It does not exist in white ginseng. It is boiled from white ginseng and turned into red ginseng, so that there is a small amount of RH 2 and Rg3, th...

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Problems solved by technology

GS has been proven to have multiple effects on the enhancement of immunity, especially in the enhancement of the differentiation activity of phagocytic cells and the increase of the concentration balance of Lysozyme in plasma. The main component of ginseng is saponin, which can improve memory function and enhance immunity. And anti-aging effect, ginsenoside RH 2 It does not exist in white ginseng. It is boiled from white ginseng and turned into red ginseng, so that there is a small amount of RH 2 and Rg3, the concentration is 0.001%, about 100,000 kg of red ginseng can produce one kg of RH 2 , Ginsenoside RH 2 It was found to have anticancer activity ten years ago, but the content was too low to meet the requirements of clinical dosage. The diol saponins and ginsenoside RH in ginseng 2 The basic structure of ginsenosides is the same, but the sugar chains are different. By decomposing and removing part of the sugar groups, the valuable ginsenoside RH can be obtained 2 , therefore, develop a kind of preparation ginsenoside RH suitable for industrialized production 2 method is a matter of great concern to the community