Miniaturized polypeptide of anti EB Virus tumour, application and preparation method

A technology for Epstein-Barr virus and tumors, applied in the field of miniaturized anti-EB virus tumor polypeptides and its application and preparation, can solve the problems of large immunogenicity, large molecular weight, adverse allergies, etc., and achieve specific targeting effects
CN1661012AInactive Publication Date: 2005-08-31PROTEIN DESIGN LAB LTD

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
PROTEIN DESIGN LAB LTD
Publication Date
2005-08-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

A miniature polypeptide resisting to EB virus tumor, its gene and its recombinant plasmid are disclosed. Its preparing process includes linking the gene for coding and leading peptide with the plasmid carrying the colicin ion channel structure domain gene, transferring engineering bacteria for amplifying, and separating and purifying by His-tag column. It can be used to kill tumor cells.
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Description

technical field

[0001] The invention relates to an anti-EB virus tumor polypeptide gene, recombinant plasmid, polypeptide and its application and preparation method. Background technique

[0002] Malignant tumors are a huge threat to human health. There are about 7 million patients who die from malignant tumors every year in the world, among which China accounts for one-sixth. Malignant tumors are the second cause of death in my country. Because its etiology, pathogenesis, and clinical manifestations have not yet been clarified, so the control effect is not ideal. Existing anti-tumor drugs play an important role in the treatment of tumors. Although they have achieved certain curative effects on some tumors, they still have defects such as poor selectivity to tumor cells, many and serious adverse reactions, and drug resistance.

[0003] In recent years, great progress has been made in the basic and clinical research of tumors, and one of the most...

Claims

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