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Medicine with chondriomere distortion preventing function

A technology for drugs and sperm, applied in the field of new pharmaceutical compositions, can solve the problems of unsafe reproduction, inability to prevent and control sperm aberrations, etc., and achieve the effect of preventing sperm aberrations

Active Publication Date: 2005-11-23
李国成
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of these can be aimed at the prevention and treatment effect of anti-sperm aberration
In addition, genetically engineered cytokines, such as bFGF, are still in the research stage as therapeutic drugs, and have not been reported to the clinic, and these growth factors have certain reproductive insecurity

Method used

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  • Medicine with chondriomere distortion preventing function

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The preparation of embodiment 1 medicine

[0024] Inoculate an appropriate amount of Cordyceps spores into the broth medium, shake and culture at 22°C for 24 hours, then spread it on a solid medium, culture it under sterile conditions for 25 days, dry it and break it into Cordyceps spore powder, and then add 300 mg Cordyceps spore powder, 65 mg of zinc gluconate (containing 8.45 mg of zinc), and 300 mg of yeast selenium (containing 0.15 mg of selenium) are evenly mixed to prepare a drug dry powder, and then mixed with 2.25 g of epimedium extract to prepare a drug combination things. Further subpackage into capsules.

Embodiment 2

[0025] Embodiment 2 Proof experiment 1 of drug action effect

[0026] The preparation method of medicine is as embodiment 1. According to different formulas, each capsule contains different amounts of Cordyceps spore powder, zinc, selenium, or epimedium extract, etc. See Table 1 for details.

[0027] Take 70 male mice and randomly divide them into 7 groups, 10 in each group. One group is the negative control group, which is fed with conventional feed every day. , wherein one group of positive control groups is fed with conventional feed every day, and the other 5 groups are groups to be tested. In addition to feeding with conventional feed every day, each mouse weighs 25g, and is fed with the pharmaceutical composition of the present invention every day. Dry powder capsules, the amount of effective drugs contained in the capsules to be administered by each group to be tested is shown in the formula column of the attached table. After feeding for 30 days, the mice were sacri...

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Abstract

The invention discloses a medicament with chondriomere distortion preventing function, wherein the medicament comprises the following raw materials (by weight portion), Chinese caterpillar fungus spore powder 2000-8000, zinc 80-120, selenium 2-3. The sperm distortion rate can be lowered by 20-25%.

Description

technical field [0001] The invention relates to the field of pharmaceutical compositions, in particular to a novel pharmaceutical composition. Background technique [0002] According to the feedback from the social and medical departments, the current situation of male infertility is becoming more and more serious. In the past 20 to 30 years, the decline in sperm quality and quantity has become a common disease in clinical practice, especially in andrology. According to the statistics of the World Health Organization (WHO) in 1987, in infertility, the female factor accounts for 39%, the male factor accounts for 20%, and about 40% of infertile men are sperm abnormalities. In the past 20 years, the number of human sperm has decreased at an average rate of 2%. According to British data reports, due to environmental pollution, drug influence, various household appliances, and electromagnetic waves and rays of different types and intensities, affected men account for about 66% o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 林剑
Owner 李国成
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