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Marsdenia tenacissima soft capsule and its preparation method

A technology of black bone vine and soft capsule, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unstable process, low quality standard, and immature preparation technology.

Inactive Publication Date: 2006-02-08
INST OF PHARMACY SHANDONG PROV ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many existing dosage forms, but the preparation process of the preparation is not mature enough, the process is unstable, and the quality standard is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0018] Example 1: Get Sclera japonica, soak for 12 hours, add water and decoct three times, for the first time for 2 hours, for the second time for 1.5 hours, for the third time for 1 hour, combine the decoction, filter, and the filtrate is concentrated to a relative density of 1.23 ( 70-80°C), dried under reduced pressure at 60°C, crushed, and passed through a 100-mesh sieve to obtain extract powder.

example 2

[0019] Example 2: Get Sclera japonica, soak for 12 hours, add water and decoct three times, for the first time for 2 hours, for the second time for 1.5 hours, for the third time for 1 hour, combine the decoction, filter, and the filtrate is concentrated to a relative density of 1.23 ( 70~80°C), add dextrin and starch in appropriate amount, mix, dry, pulverize, and pass through a 100-mesh sieve to obtain extract powder.

example 3

[0020] Example 3: Grind and mix uniformly to make the contents of the soft capsule by adding 50% of Aegypti japonica extract powder, 47% of salad oil, 1.5% of beeswax, 1% of vitamin E, and 0.5% of preservative; add an appropriate amount of gelatin into a stainless steel sol tank Add 1:1 water, airtight, soak, and heat to 70°C to dissolve the gelatin. According to the ratio of glycerin and gelatin 0.4:1, add glycerin, stir, vacuumize to remove air bubbles, and put it in a gelatin insulation bucket Keep it warm at 70°C to make a capsule material; make a soft capsule by pressing.

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PUM

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Abstract

The invention provides a Marsdenia tenacissima soft capsule, which comprises Marsdenia tenacissima extract and other auxiliary materials including medium, stabilizer, aging retarder and preservative agent.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines and belongs to the improvement technology of traditional Chinese medicine preparations. technical background [0002] Xiaoai Tablets are Chinese patent medicines with anti-cancer, anti-inflammatory and asthma-relieving effects. They are used for esophageal cancer, gastric cancer, and lung cancer. They also have certain curative effects on various malignant tumors such as colorectal cancer, cervical cancer, and leukemia. Treatment after radiotherapy, chemotherapy and surgery. And for the treatment of chronic tracheitis and bronchial asthma. The main drug is Scytheca sinensis, and there is serious homonym phenomenon. The plant name is Tongguangsan (Marsdenia tenacissima (Roxb.) Wight et Arn.; Asclepiastenacissima Roxb.; Metaplexis cavaleriei Lev.; .ex Woodson); the medicinal material is called Black Bone Teng, (pull) Caulis Marsdeniae Tenacissimae, (English) Tenacious Condorvine Stem; ...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K9/48A61P35/00
Inventor 仲英刘鲁庄建红王菊王姣孙敬勇贾志伟左春旭
Owner INST OF PHARMACY SHANDONG PROV ACAD OF MEDICAL SCI
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