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Anticancer Chinese medicine compound preparation and its making method thereof

A traditional Chinese medicine preparation, the technology of traditional Chinese medicine, applied in the direction of anti-tumor drugs, pharmaceutical formulations, drug delivery, etc., can solve the problems of treating the symptoms but not the root cause, the curative effect is not exact, and the use of expensive ingredients, etc.

Inactive Publication Date: 2006-03-15
烟台同泰药物研究有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, with the deepening of clinical research, some traditional Chinese medicines for the treatment of malignant tumors have also appeared on the market, but some of the existing medicines treat the symptoms but not the root cause, some use expensive ingredients, and some are discontinued due to inaccurate curative effects during the application process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] It is characterized in that it contains four kinds of traditional Chinese medicines, ginseng, javanica, curcuma and coix seed. (Prescription①)

[0090] The preparation of the injection is as follows:

[0091] The preparation method of the active ingredient of ginseng is as follows: take 1200 g of ginseng medicinal materials, add water to decoct twice, and add water respectively to 8 times and 6 times the amount each time, and the extract is centrifuged through a tubular centrifuge, and the centrifuge is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 70% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recover ethanol from the extract, concentrate into a paste, and dry to obtain 22.1 g of active ingredients of ginseng. Take the macroporous resi...

Embodiment 2

[0103] It is characterized in that it contains five kinds of traditional Chinese medicines: ginseng, Brucea javanica, curcuma, coix seed and mylabris. (prescription ②)

[0104] The preparation of the injection is as follows:

[0105] The preparation method of the active ingredient of ginseng is as follows: take 1200 g of ginseng medicinal materials, add water to decoct twice, and add water respectively to 8 times and 6 times the amount each time, and the extract is centrifuged through a tubular centrifuge, and the centrifuge is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 70% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recovery of ethanol from the extract, concentration into a paste, and drying to obtain 21.8 g of active ingredients of ginseng....

Embodiment 3

[0119] It is characterized in that it contains five kinds of traditional Chinese medicines, ginseng, javanica, curcuma, coix seed and toad. (prescription ③)

[0120] The preparation of the injection is as follows:

[0121] The preparation method of the active ingredient of ginseng is as follows: take 1200 g of ginseng medicinal materials, add water to decoct twice, and add water respectively to 8 times and 6 times the amount each time, and the extract is centrifuged through a tubular centrifuge, and the centrifuge is passed through D 101 Adsorption by macroporous resin, collect the effluent, and store in another container; wash the macroporous resin with water until the effluent is light-colored, then elute with 70% ethanol, collect the eluate, concentrate under reduced pressure, spray dry, use 90% ethanol for dry powder Reflux extraction, recovery of ethanol from the extract, concentration into a paste, and drying to obtain 20.9 g of active ingredients of ginseng. Take the ...

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Abstract

An anticancer Chinese medicine is prepared from ginseng, brucea fruit, zedoary oil and coix seed. It is possible to use other Chinese-medicinal materials as its raw materials for regulating its action. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to an anticancer traditional Chinese medicine compound preparation and a preparation method, which is characterized in that the compound preparation is made of traditional Chinese medicine raw materials ginseng, javanica bruceae, curcuma oil and coix seed, and other traditional Chinese medicines can be added to the preparation to adjust its effect as required. Background technique: [0002] According to the research of the National Cancer Prevention and Research Office on the death trend of malignant tumors in my country in the past 20 years, the adjusted mortality rate of malignant tumors in my country was 84.58 / 100,000 in the 1970s and 94.36 / 100,000 in the 1990s, an increase of 11.56%. The main malignant tumors that have risen are: gastric cancer (9.95%), liver cancer (41.17%), lung cancer (111.85%) and leukemia (30.26%), which pose a huge threat to the life of the patient and seriously affect the quality of life. a heavy burde...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/00A61P35/00
Inventor 刘智谋刘露严轶东
Owner 烟台同泰药物研究有限公司
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